There is really nothing complicated about doing a phage cross, you just coinfect a host with both phage types and then screen the progeny for recombinants. Generally an MOI of around 1 for each would be fine. However note that the phages need to have some homology in order to recombine, if you cross two phages that are entirely unrelated then you won't get any recombinants out.
Presumably you have some specific phenotype that you wish to screen for, be sure this is something that will be readily detectable.
@Michael J. Benedik Thank you very much for your help, what I am looking for is to cross phages with each other, in order to increase the host range on multiresistant strains of klebsiella, I am new to these issues and it is costing me a little to have results.
I am not really clear on what you are trying to do. A phage cross, assuming the phages are similar and able to recombine, might be able to trade host specificity. In other words if phage A binds to receptor A and phage B binds to receptor B, you might be able to generate a phage A that binds to receptor B assuming that otherwise the phages are similar. But a cross is probably not going to extend host range, just exchange it.
But if you have a multiple resistant strain of Klebsiella that is of particular interest, have you just screened de novo for new phages that can infect and kill that strain. So you may not need a cross just a new phage that you could make more virulent by mutation (if needed).
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