What are the pretrained-language-model that is obviously better than BERT and RoBERTa?

19 January 2021 602 2 View

Can I design an aptamer that can sense microbial activity?

I am trying to design a boron nitride based biosensor that can sense the abnormality of microbial activities on fish skin. I am very curious that is it possible to have such an aptamer that can...

23 September 2020 6,352 4 View

Can I build a stable cell line for CO-IP?

I want to know two protein interactions via CO-IP, and one of the proteins has several different mutations. I need to transfect all these mutations into HEK293T cells for doing Co-IP every time,...

03 September 2020 342 3 View

Based on transformer, how to improve the text generation results?

If I do not pretrain the text generation model like BART, how to improve the result based on transformer like tensor2tensor? What are the improvement ideas for transformer in text generation task?

18 August 2020 7,265 3 View

Are there any deep models that are better than BERT-CRF in NER task?

Named entity recognition (NER) is task that mark tags of the input text sequence. BERT-CRF is a good NER model. I want to find a better NER model. Or I want to improve the BERT-CRF model. What...

18 August 2020 7,070 2 View

What are the effects of gender of performer on animal?

I remember a paper studied the effects of gender of handler on animal (mouse?) showing that male handler has more negative effects on animal (for example, causing animal anxious) compared to...

05 August 2020 4,131 1 View

Question of pretraining text-generation task, it seems that pretraining is not work for a small model?

My task is to generate keywords from sentences. I pretrain a text-generation model. I mask the sentences' tokens and predict the whole sentences' tokens. Pretraining batch_size = 8 and step =...

28 July 2020 5,675 1 View

How to tackle endogenous problems with "truncated" data structure?

When I want to estimate educational return, I run a regression like: ln(wage)=beta1+beta2*education+other control variables+u In order to tackle the endogenous problems induced by potential...

21 June 2020 2,244 1 View

What is the principle of Unsupervised Data Augmentation (UDA)? Why does UDA work?

UDA(https://github.com/google-research/uda) could achieve good accuracy by only 20 training data on text classification. But I find it is hard to reproduce the result on my own dataset. So I...

05 June 2020 1,486 2 View

What are the simplest methods for the label noise problem?

If I have enough low quality data from unsupervised methods or rule-based methods. Do you think removing the wrong data predicted by trained model is a simple but effective method?

02 June 2020 4,078 3 View

After a reference from Int J Body Compos Res, can any body help?

Hi, I am after the reference below, my library says it cannot obtain a copy either locally or internationally, any help appreciated! Chris Wang ZM, Heshka S, Wielopolski L, Pi-Sunyer FX, Pierson...

03 March 2021 6,193 1 View

I can detect my protein but the encoding DNA sequence has stop codons within. Should I ignore the stop codons?

I constructed a synthetic DNA library (scFv, VH-VL orientation) with a 3' reporter and 8x histag. I cloned and expressed this gene following which I performed an ELISA. The ELISA results suggested...

19 February 2021 7,006 5 View

How do I check the quality of my viral RNA prior to metagenomic sequencing?

I am doing metagenomic sequencing without enrichment for an RNA virus. After my RNA is extracted from the blood I am doing library prep with the NEBNext Ultra directional RNA library prep kit for...

16 February 2021 5,101 2 View

How to remove the species data from rda data frame in R (only remain the sites/samples point)?

Dear everyone, When I using the rda function in r, I met this question. As you can see in the figure, there are a lot of deep blue points which refers to the species. But I would like remain...

15 February 2021 8,982 2 View

What recipe of homemade lenti-virus concentrator do you use?

My lab is using a lenti-X concentrator. And we are looking for a homemade recipe. I have tried this recipe....

08 February 2021 5,965 1 View

How to find statistical data of EEG signals?

Hi all, I hope everyone is doing good. I am working on Machine Learning, I am working on EEG data for which I have to extract statistical features of the data. Using mne library I have extracted...

29 January 2021 6,686 1 View

How can you adjust pH of SM buffer?

Good afternoon, please how can you adjust pH of phage SM buffer? I presume that main ingredient that has influence of pH is Tris/HCl buffer, but according to literature its range of pH is from 7...

27 January 2021 5,767 3 View

What is the composition of TM buffer used for concentrating bacteriophage?

Hello everyone, I have to isolate DNA from Brucella phage , but before that, I have to concentrate the phage using PEG 8000. I have got protocol for concentrating the phage using PEG and TM buffer...

24 January 2021 2,767 6 View

How can I solve this problem with agarose gel DNA purification of bigger (1-4kb) fragments ?

Hi everyone, I perform a PCR + Restriction Digestion (single cut, same at both sides) over a metagenomic library. After that, I am trying to purifiy DNA fragments between 1-4kbp long from the...

24 January 2021 2,190 5 View

Is PV array not available in MATLAb 2020a simulink?

I have MATLAB 2020a. PV array is not present in the simulink library. Can anyone please explain if the name of module has been changed or is it not available anymore? Is there any way to add PV...

24 January 2021 7,962 5 View