How is it that rbc production induces hypoxia in fish?

13 January 2014 1 510 Report

I am working on hematotoxicity in fish with heavy metals. In one of the papers I read, it said that if haemoglobin and haematocrit increased, then it causes hypoxia in fish. I think that an increase in Hb means an increase in oxygen carrying capacity. Could anybody clarify how an increase in blood parameters causes hypoxia?

Sk Jha

I am not sure of my answer but a possible explanation can be as below

The amount of oxygen from gills of fish may be limited. If there is more of RBC & as the saturation of individual rbc by limited oxygen will be inversely proportional to the number. & the peripheral delivery of oxygen is directly proportional to the oxygen saturation of individual rbc.

So more of rbc, less delivery of oxygen to tissue.

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