How does bis(4-nitrophenyl)-phosphate (BNPP) act in chemotherapy?

More Nupur Raychaudhuri's questions See All

I am trying to subculture my isolated yeast strain from it's mother culture YPD medium plate. But its not growing at all. How to subculture it again?

I have tried with different media. But its not showing any result. Yeast strain Medium used: Yeast extract Peptone Dextrose Agar, Sabouraud Dextrose agar, Yeast extract Peptone Sucrose Agar.

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Does Napabucasin soluble in dichloromethane and in ethanol?

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How optimize the Size Exclusion Chromatography?

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01 March 2021 2,215 2 View

Could you please recommend some good journal that accept very long revie papers (approximately 6000+ words) in neurosurgery, cancer biology ?

01 March 2021 8,087 3 View

Which cell line should we use to perform biological dosimetry experiments?

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What is the state of the drug inside solid lipid nanoparticles (SLNs)?

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Is CD44 degraded in lysosome together with hyaluronan after CD44 mediated endocytosis of hyaluronic acid?

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How does an antibody have full intact antibody + half antibody?

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How do I choose contrasts in SPM8?

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Is it possible that Cancer cells could survive in heparinized blood for 48 hours?

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23 February 2021 3,840 3 View

Does anyone have any ideas why drug-resistant malaria is increasing in Southeast Asia even when those drugs are no longer used?

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Cristiano Ferlini

BNPP is a specific inhibitor of carboxylesterase (CE). BNPP affects the metanolism of chemo such as Topo-I inhibitors and has been used in animal models to modulate the effects of chemotherapy when CE activity is high.

http://imr.sagepub.com/content/33/1/84.full.pdf

Nupur Raychaudhuri

Thank you Cristiano.