Cancer

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Questions related to Cancer

Algebraic solution of Maxwell's equations?

At least some differential equations have the equivalent algebraic expressions. The sets of such (partial) equations are not excluded.

20 June 2024 4,296 4 View

Hi All, about multiplex immunofluorescence,what could be the reasons for unwated flurophore background ? other than autofluorescence and 1ry Ab conc?

Could the tissue quality/age be an issue ??

16 June 2024 7,783 0 View

How to adjust or recalibrate negative MFI values from cytometer?

I am looking at puromycin incorporation rate by flow cytometry using a specific anti-puro-antibody which I use to stain different cell types. For some cells the signal is high (i.e. Puro MFI),...

13 June 2024 1,138 1 View

The problem at hand concerns the application of the "II Lagrange's formula". Would you like to try solving it?

In triangle ABC, the bisector AL₁ is drawn. Points O₁, O₂, O are the centers of the circles circumscribed around triangles ACL₁, ABL₁, ABC, respectively. The radii are denoted as R₁, R₂, R for...

13 June 2024 7,627 1 View

What are the answers to Epidemiology Question including revalence, case fatality etc ?

Suppose that in January 1996, 1000 adult residents of a community accepted an invitation to be examined for hypothyroidism at a local clinic. Eight persons were found to have the disease, it was...

28 May 2024 6,967 7 View

What happens to general relativity time operates differently in gravitational fields & difference between general relativity & special relativity?

What happens according to general relativity time operates differently in gravitational fields and difference between general relativity and special relativity?

02 May 2024 788 2 View

Lesson study approach as a teacher development model for grade 6 mathematics teachers: A case of suing long division method?

Lesson study teacher development approach

14 February 2024 6,964 0 View

Could you please provide details on the optimal Lipofectamine 3000 transfection protocol for efficiently delivering a plasmid into CaSki cells?

Dear colleagues, I need to transfect a 10 kb plasmid into Caski cells and am hoping to use Lipofectamine 3000 for the transfection. If anyone has experience using Lipofectamine 3000 specifically...

12 January 2024 1,780 1 View

Journal article request please ?

Tous-Espelosin, M. et al. (2023) ‘“It Helped Me to Disconnect My Mind from the Problems”: The Subjective Experiences of People with Schizophrenia Taking Part in a Concurrent Exercise Program’,...

18 December 2023 862 2 View

Conjunction of autocorrelated residuals and factor analysis/SEM in psychometrics?

Basically most studies of "structural equation modelling + time-series data" focus on longitudinal datasets (e.g., (residual) dynamic SEM). However, for a questionnaire survey or measure at a...

22 November 2023 8,003 0 View

What practical hurdles for Lentivirus-Tiam1 therapy?

Lentivirus-Mediated Gene Delivery is a common method for introducing therapeutic genes into cancer cells. One such gene is Tiam1, known for its potential impact on cancer cell behavior.

17 August 2023 2,405 1 View

Which human cell lines are best for invitro toxicity screening for drug in local musculoskeletal (mainly bone & muscle) application?

I need to screen the toxicity of several compounds that will be applied locally to an open wound of bone and muscle injury, which human cell lines (good for several passages) would be most...

27 July 2023 4,837 4 View

Should we divide the data among exploratory factor analysis and exploratory factor analysis or is the same data is used for both?

I'm doing a validation study and for construct validity, I'll analyze my data through EFA and CFA. So, the same data should be used in both processes or should we divide the data? And if we divide...

08 June 2023 7,065 5 View

What kind of cell culture contamination could this be?

Dear all, since a few weeks, we have been noticing the following 'stuff' swimming in our flasks (see images attached). The cells we use are self-isolated primary human keratinocytes. They are...

11 May 2023 9,127 0 View

Do microorganisms use to remove pollutants that contaminate water soil&air&process of converting environmentalpollutants toharmlessproductsbymicrobes?

Do microorganisms use to remove pollutants that contaminate our water soil & air & process of converting environmental pollutants to harmless products by microbes?

03 April 2023 4,691 4 View

Methods for calculating adjusted incidence rates using validation statistics?

I am looking for advice on methods for adjusting incidence rates based on data obtained from validation studies (i.e., sensitivity, specificity values). Any insight you can provide would be helpful!

06 December 2022 9,108 4 View

What are my phage contaminated with?

I'm having trouble getting clear images of my bacteriophage under TEM. The process I've followed thus far is described below. Any help would be appreciated. I've isolated bacteriophage active...

13 December 2021 8,439 3 View

How to best establish change in one group pre-/post design with small sample?

Hello everyone. I am planning a one-group pre-/post test design (I am aware of the limitations, including a control group is unfortuntately not feasible) and want to measure whether var 1...

21 August 2021 1,892 4 View

How to reuse a MTT treated metallic sample?

I have performed MTT assay on Ti samples and now I want to reuse those samples, can anyone guide me how I clean the samples and re-use it. Thanks

07 August 2021 2,103 5 View

Why a drug containing functionalized silver nano-particles shows highly varied response against MCF-7 Breast Cancer in NOD-SCID mouse group?

In an in-vivo study against MCF-7 Breast cancer, it was observed that the response to the targeted drug containing surface engineered silver nanoparticles was highly different in three mice as...

17 May 2021 4,013 10 View

What is the difference between human umbilical vein endothelial cells (HUVECs) and bone marrow endothelial cells?

Hello I am new to work on endothelial cells, and I have been reading about them a lot and trying to know the difference between human umbilical vein endothelial cells (HUVECs) and bone marrow...

29 January 2021 9,016 4 View

Allelic expression and total gene expression contradict?

Hi, I am looking at a SNP located within the 3'UTR of a gene of interest. I discovered that in a tissue type of interet one of the alleles of the SNP is preferentially expressed over the other in...

23 November 2020 9,709 0 View

Is there any latest updated tool For download TCGA cancer dataset ?

Previously "TCGA2STAT" a tool of R is used to download TCGA cancer data and their corresponding normal samples, but this tool is deprecated now. Now I need to download a lot of cancer samples as...

12 November 2020 1,008 5 View

Whis HLA-A2 TAAs are best for DC pulsation and CD8+ cytotoxic T cell induction?

When looking to establish Ag-specific CD8 cytotoxic T cells with autologous dendritic cells, there are numerous tumor-associated Ags to choose from. Does anybody know which Ags give the best...

28 October 2020 2,301 2 View

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