Actually I have collected some cell line from literature review like CaCo2, HUVEC, RAECs, HEK293. So can anyone suggest me more cell line for Angiotensin Converting Enzyme and Carbonic Anhydrase 1 pathways?
I am not an expert in this field, but I am very interested and have researched to find an answer. I received some assistance from tlooto.com for this response. Could you please review the response below to see if it is correct?
To explore the Angiotensin-Converting Enzyme (ACE) and Carbonic Anhydrase 1 (CA1) pathways for blood pressure regulation, consider using the following cell lines in addition to CaCo2, HUVEC, RAECs, and HEK293:
Human Aortic Endothelial Cells (HAECs): Suitable for vascular studies and ACE expression [2].
Human Kidney Cells (HK-2): Important for renal pathway research related to ACE and CA1 [1].
Human Microvascular Endothelial Cells (HMVECs): Effective for studying microvascular aspects of blood pressure regulation [2].
Human B-cell Lymphoma Cell Lines (Raji, Ramos): Relevant for studying CA1 in relation to extracellular acidosis [3].
These cell lines provide a comprehensive platform for investigating the mechanisms underlying blood pressure regulation through the ACE and CA1 pathways.
Reference
[1]Chen, L. Q., Howison, C., Spier, C., Stopeck, A., Malm, S. W., Pagel, M., & Baker, A. (2015). Assessment of carbonic anhydrase IX expression and extracellular pH in B-cell lymphoma cell line models. Leukemia & Lymphoma, 56, 1432 - 1439.
[2]Chen, R., Suchard, M., Krumholz, H., Schuemie, M., Shea, S., Duke, J., Pratt, N., Reich, C., Madigan, D., You, S., Ryan, P., & Hripcsak, G. (2021). Comparative First-Line Effectiveness and Safety of ACE (Angiotensin-Converting Enzyme) Inhibitors and Angiotensin Receptor Blockers. Hypertension, 78, 591 - 603.
[3]Altamimi, S., Khalil, A., Khalaiwi, K. A., Milner, R., Pusic, M. V., & Othman, M. A. (2010). First-line drugs for hypertension. São Paulo Medical Journal, 128, 47 - 47.