Does MDA-MB-231 require any stimulation(like by Interferone gamma) to express PD-L1 or it constitutively express PD-L1 ?

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Malcolm Nobre

Hello Ananya,

MDA-MB-231 is a basal B TNBC cell line which expresses greater levels of PD-L1 constitutively as well as with interferon gamma.

You may want to refer to the paper attached below for more information.

Article PD-L1 Expression Is Increased in a Subset of Basal Type Brea...

Best

Ananya Chatterjee

Thank you Malcolm Nobre

Taufeeque Ali

MDA-MB-231 cells presented uniformly high expression of PD-L1 regardless of the culture conditions.

Article PD-L1 CAR effector cells induce self-amplifying cytotoxic ef...