I am looking for identified MHC-I epitopes in 4T1 murine breast cancer cell line that can be used in a therapeutic vaccine, couldn't find something useful in literature so far ! Any known papers or studies please ?
4T1 expresses the gp70/AH1 antigen. For therapeutic vaccination, you can use the AH5 variant of this epitope to generate greater numbers of T cells than with AH1 vaccination.