01 January 1970 1 2K Report

Dear all,

I want to set the experiment that the phosphorylation of my target protein in human cancer cell lines cannot be activated by the gene editing method.

How can I achieve this?

In simple, I am always think about how to change the status of phosphorylation of target protein using gene editing procedure, such as plasmid construction, CRISPR-CAS9, or other methods.

Thank you sincerely advance for your kind answers.

Dr. Zhou

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