While reading an old paper (https://core.ac.uk/download/pdf/82090013.pdf , 1995) about a similar virus to the one Im working with, I read they found a binding site for VBP (https://www.uniprot.org/uniprot/Q92172). But the binding sequence in the paper and in uniprot are very different (TT[G/A]CATAAG vs GTTTACATAAAC). Furthermore, Alggen cant find VBP binding sequences in the same sequence they used in that paper of 1995 (Prague C RSV).
If I copy the motif they indicate in the 1995 paper and search it in the RSV sequence, I find several results in the complementary strand but not in the direct strand.
So my questions would be two:
Can TBS work in the complementary strand?
How can this big difference in motif between the paper and the current databases be explained?
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