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Questions related to Animal Models
Application of stem cell on Spinal Cord Injury animal model
28 September 2017 3,639 2 View
I'm doing research on formulation development of chewable tablet. What animal model i should use?
27 September 2017 2,759 1 View
Which is the appropriate and suitable animal model of Inflammatory Bowel Syndrome for screening of probiotics?
24 September 2017 4,194 1 View
There is no definite models exist to reproduce the Alzheimer's disease in animals which resembles human. Is there any suitable models tell us..
12 August 2017 8,168 13 View
I have been reading about various drugs inducing anti-remodeling effects in animal models (rats) of myocardial infarction. Can someone suggest why ischemia-reperfusion is not preferred in this...
16 March 2017 7,437 4 View
There are different transgenic rat models with on-off switching genes but I would like to know which of them have early alterations in behavioural tasks.
15 March 2017 357 2 View
I diluted cisplatin according to the manufacturer and previous articles (diluted with normal saline with concentration 1mg/ml). However there was little precipitation occurred after dilution....
28 February 2017 5,919 2 View
Does anyone has the same issue of the relative low survival rate of the obese mice after surgery? My mice were anesthetized by ketamine and xyline. I also give the pain killer (Buprenophine)...
21 February 2017 2,250 5 View
I would be interested in learning what research tools are out there to study mesenteric adipocytes? Either in cell culture, animal models (e.g. mouse) or in human tissue? I would be happy for any...
17 February 2017 6,785 1 View
The idea is to evaluate the effects of different treatments on bone healing in animals but studies were realized on several animal models. Can I compare the outcome (i.e. Bone bridging or Bone...
25 January 2017 5,494 2 View
Hi all. Is anybody of you experienced with measuring folate levels in mouse plasma? If yes, which method do you usually use and what levels do you expect in a healthy adult mouse? Thanks lots for...
06 January 2017 6,663 2 View
I am thinking of doing in utero injections of mice to study the effects of a drug on the embryos. However, we hope to use the female mice again after it gives birth to the injected pups. Is it...
03 January 2017 1,066 4 View
Hello, I am trying to make phototrombotic ischemic stroke mouse model. The procedure is 1. Intraperitoneal injection of Rose bengal 50ug/mouse weight (g) 2. After 5 min, switch on the cold light...
22 December 2016 8,493 4 View
Is there any alternate animal model for type II collagen induced arthritis in DBA/1 mice? DBA/1 mice is not available easily and thus suggestion on any preferred animal model for the study is...
20 December 2016 5,155 2 View
Research finds that Sprague-Dawley rats often develop spontaneous tumors by 2 years of age (Prejean et al., 1973). Can anybody share photographs of an SD rat, raised as a healthy control, that...
16 December 2016 4,567 3 View
Where and how to buy zika virus (ZIKV) or mouse-adapted ZIKV strain?
30 November 2016 3,521 2 View
I am trying to find other animal model study other than tail bleeding assay to analyze pharmacodynamics in hemophilia A mouse model (FVIII KO). I am aware of transection model, however I want to...
30 November 2016 7,262 1 View
I am looking to administer estriol over a long period of time (more than a year) and am considering the use of topical creams. Has anyone used this method or know of a paper or lab that has used...
23 November 2016 9,240 3 View
We are doing an experiment where mice must eat a highly preferred food, which has been manipulated to have an unpleasant taste. We planned to use quinine but it may not arrive in time for...
19 November 2016 9,808 3 View
I need to feed the rat with powder high fat diet. We used to mix the powder high fat diet with coconut oil and make the powder diet into small balls. But, the rats are not eating these balls...
17 November 2016 6,496 5 View
I would like to know the potential of HCT116 cells for developing subcutaneous tumor in nude mice. I want to perform a study in which I am plannng to inject 5 X 10^6 HCT116 cells subcutaneously on...
10 November 2016 8,485 7 View
Or what is the ideal body weight range for SD rats to induce hyperlipidemia? Some used SD rats with body weight over 300 g, some used SD rats with body weight around 120-150g? Some used body...
09 November 2016 8,529 2 View
Can we get them already mature (several month old)?
07 November 2016 2,060 1 View
Hello everyone, I performed IP injection of mouse cancer cells (GL261, 75.000 cells) in C57bl/6 mice. However, three weeks after, mice started to be moribund and necessitated to be sacrificed....
03 November 2016 4,498 3 View