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Questions related to Animal Models
Hi all, I'm looking for a paper that gives details about object perception in somatosensory cortex (barrel cortex) of rats. I didn't find a paper taking about object perception in barrel cortex....
07 July 2016 1,427 1 View
In order to estimate the therapeutic efficacy of 90Y or 177Lu targeted to tumors in patients or to estimate the total amount of radioactivity that needs to be injected into a patient, what is the...
07 July 2016 2,222 2 View
I've operated left side and collected left part of the brain and I've been used RIPA buffer for homogenization and centrifuged at 10,000 rpm for 20 min,the occlusion period is 60 min.all my 24hr...
07 July 2016 1,992 2 View
Hi all, I am doing double marker IHC with anti Iba-1 (goat IgG) and MHC-II (Mouse IgG2b) antibody in frozen section of human retina. In my single marker IHC, both antibody stains different cell...
07 July 2016 8,889 4 View
What is the best method for the hypophysecomy?
07 July 2016 7,530 3 View
We hypothesis that chronic biliary pancreatitis is associated with pancreatic cancer initiation. But we are stucked in setting up an animal model. Bile infusion method can be used in acute...
07 July 2016 4,742 1 View
I want to dissolve DMBA in corn oil or sesame oil to oral feed the mouse to induce mammary tumor, according to many protocols published. But the question is how to dissolve DMBA in oil? Should...
07 July 2016 7,663 3 View
Hello everyone, I wondered why NOD-Scid mice are suffering of irradiation exposure and nude mice not? I performed half brain irradiation in NOD-Scid model and after 5 days, all mice started to...
15 June 2016 10,017 5 View
Hello, I need to generate tumors in nude mice with the cell lines SK MEL 28 (melanoma) and MDA MB 231 (breast cancer), both human tumoral cell lines. How many cells do i have to inject...
10 June 2016 9,798 3 View
I want to examine effect of calcium deficiency in fertility of female mouse. i need a protocol for creating calcium deficiency.
06 June 2016 9,922 3 View
Sometimes my animals will stay put on one corner of the chamber. Is it ok to repeat a trial with the same animal, while counterbalancing the sides to avoid familiarity with the...
06 June 2016 9,362 7 View
I did not find any resource.
06 June 2016 7,768 3 View
I would like to know why we need to include a healthy animal group? For example: If I have 3 groups: 1st group is a tumour induced mice treated with a non-targeted drug. 2nd group is a tumour...
06 June 2016 5,728 8 View
06 June 2016 8,416 6 View
06 June 2016 3,502 4 View
How to do protein analysis from animal liver or blood? Do i need to mash the liver first? If anyone familiar with the protocol hope can share with me.
06 June 2016 2,275 4 View
I'm currently working on absorption of a low molecular weight protein. After radiolabelling, I injected the protein into two animal models, an healthy one (balb/c male) and one bearing two tumours...
06 June 2016 4,703 1 View
Hi everyone, I am having a challenge to punch the mouse hippocampus. Does anybody have experience in this area and can help?
06 June 2016 1,578 4 View
01 June 2016 5,977 1 View
I have a mutant zebrafish strain that likely has hypothryoidism as a result of the mutation. I am basing this on the fact that the adults are dwarfs compared to wild type fish and also do not...
31 May 2016 6,464 2 View
Currently I am working on a project relating effect of some herbal medicine on the extent physical fitness in animal model. And in this purpose I need to monitor the oxygen consumption rate and...
25 May 2016 8,822 2 View
I know that mice are disqualified if they don't interact for at least 30 seconds during the test. I am wondering if there is literature on rats and what is considered too little interaction?
20 May 2016 6,633 3 View
I need to perform experiments on genetically autophagy-deficient mice,which mutants can you suggest to me ? Thank you !
09 May 2016 6,031 3 View
or any other animal model
06 May 2016 8,181 2 View