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Questions related to Animal Models
Hi everyone We are currently working on rats models of vascular calcification, in particular medial arterial calcification . Are there any large animal models such as pig or sheep to study this...
09 July 2015 2,890 3 View
autoimmunity is said to be one of the cause for vitiligo disorder,if any stardard animal models are there for vitiligo kindly reply me with help of articles
07 July 2015 8,601 2 View
pain
07 July 2015 3,584 1 View
I am tirying to feed the rat with rat chow supplemented with 2% cholesterol, 1% cholic acid for making hypercholesterolemic rat model. However, it is difficult to dissolve cholic acid. As the last...
07 July 2015 6,394 5 View
Hello, I have read in many papers, they used mice to study pharmacokinetics of liposomal doxorubicin, scientists also used rat for the same purpose. is it okay to use mice for a cytotoxic drug....
07 July 2015 2,955 3 View
07 July 2015 8,608 3 View
I’m using the reporter mouse strains ROSA26eYFP to monitor Cre recombinase-mediated excision in vivo. However, since I’m using also the same locus to overexpress a protein, I want to know if you...
07 July 2015 8,384 2 View
06 July 2015 506 2 View
I am looking for the drugs that can activate Hypoxia Inducible Factors in kidney. Usually used drugs are prolyl hydroxylase inhibitors. I shall choose one of them to use in mice with a long period...
06 June 2015 6,093 14 View
It is well known that Alloxan and streptotocin cause type 1 diabetes mellitus due to damage of beta pancreatic cells.But, what are the animal models that can be used to study the effect of some...
06 June 2015 1,871 16 View
STZ induction mouse or rat ? how about NOD mouse or BB rat? Is there any method for viral induction ? which one will be closest to mimic natural b cell destruction ?
06 June 2015 7,322 5 View
Dear All We have recently developed some new mineral-based hemostatic agents. As an ideal haemostatic agent should not present negative effects on the fresh wound and its healing process, we used...
06 June 2015 4,218 5 View
I gave hamsters prion infection about 40 days ago. So with 263 strain signs should appear after approximately 60 plus days. Now, one of the hamsters is having movement problems in forelegs and it...
27 May 2015 9,656 3 View
we are going to test a type of stem cells in a specific disease and expecting the results after six months. Is just not observing any abnormal signs and -of course- deaths in the models enough to...
26 May 2015 5,228 3 View
Hi, I'm doing a study on cartilage restoration and I used male new zealand white rabbits for the in vivo experiment. Many articles that I come across used male rabbits as well. But I've been asked...
26 May 2015 1,422 1 View
We are working on a drug for which dose in rat is difficult to find in literature. But we do have dose in humans. We are in search of article or guideline stating conversion from human dose to...
19 May 2015 2,350 1 View
we are conducting a lab research to test a type of stem cells in the retinitis pigmentosa. I want to know which animal model is the most suitable for the research.I know it may depend only upon...
05 May 2015 4,387 10 View
05 May 2015 4,612 2 View
Wish to know more specific details about a mouse or rat model for PTSD.
05 May 2015 2,698 4 View
05 May 2015 8,127 1 View
05 May 2015 9,624 4 View
We wish to evaluate the efficacy of our anti-cancer nanoformulation in a transferrin over-expressed tumor animal model. What murine cell lines can be used to induce the same in BALB/C and C57BL/6...
05 May 2015 3,116 2 View
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05 May 2015 5,798 2 View
05 May 2015 5,549 4 View