It is said that community based-studies are required to identify the societal risk factors such as age, sex, occupation and number of donation that are significantly associated with TTI despite of the strict screening and testing practice. The question in mind is - are there any ways to detect early on the blood donors who are at a high risk of having TTI compared to those blood donors who have regular type of blood in order to help in reducing the burden of TTI in blood banking?
Reference: Shiferaw, E., Tadilo, W., Melkie, I., & Shiferaw, M. (2019). Sero-prevalence and trends of transfusion-transmissible infections among blood donors at Bahir Dar district blood bank, northwest Ethiopia: A four year retrospective study. PLOS ONE, 14(4), e0214755. https://doi.org/10.1371/journal.pone.0214755
There are several ways to identify high-risk donors who are more likely to transmit transfusion-transmissible infections (TTI) through donated blood.
References:
World Health Organization. (n.d.). Screening Donated Blood for Transfusion-Transmissible Infections. WHO-Recommendations. https://apps.who.int/iris/rest/bitstreams/52580/retrieve
World Health Organization. (2012). TTI and donor risk assessment. Blood Donor Selection - NCBI Bookshelf. https://www.ncbi.nlm.nih.gov/books/NBK138223/#:~:text=Prospective%20donors%20should%20be%20asked,and%20possible%20exposure%20to%20infection.
To reduce the possibility of infection spreading via the transfusion route:
Reference:
World Health Organization (2009). Screening for transfusion-transmissible infections. National Library of Medication. https://www.ncbi.nlm.nih.gov/books/NBK142989/.
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