Hi, I'm analyzing microsatellite data and used both the R packages genepop and poppr to calculate the null allele values. But I get completely different values. Is this expected? do the packages calculate the null allele values differently? thanks
There are different methods to estimate null alleles, mostly assuming HWE. genepop uses the techniques of Dempster et al. (1977), and other programs use other methods. Read this paper for methods comparison.
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