Hello, how can I do the statistics associated with genotypes and alleles as in the table? thank you very much for your attention.
First, you need to build your genotype database in a numeric format (i.e. TT=0, TC=1, CC=2, control=0, patient=1, etc) and then use a logistic regression analysis with odd ratios. Just remember that response variable has to be dichotomous (i.e. control=0, patient=1).
To analyze genotype and allele distribution statistics, follow these steps:
1. Collect Data: Gather genotype data for your study population.
2. Calculate Allele Frequencies: Count the occurrences of each allele and divide by the total number of alleles.
3. Determine Genotype Frequencies: Count the occurrences of each genotype and divide by the total number of individuals.
4. Perform Statistical Tests: Use tests like the Hardy-Weinberg equilibrium to check if allele frequencies are consistent with expected values.
You can use software like R or Python with relevant packages to automate these calculations and generate statistics.
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