Are any database collected cell penetrating anticancer peptides ?

Dear researchers, Anticancer peptides(ACPs) with cell-penetrating properties can enter to cytoplasmic space of cancer cells and induce cell death. but, I could not find the database that...

29 January 2021 707 3 View

How to calculate DNA concentration of a sample with high concentration buffer?

I want to calculate the concentration of DNA in an unknown sample. But it's buffer has a high concentration and our nanodrop don't accept that as a blank of dsDNA. Thus I dilute the buffer with...

23 January 2021 9,440 2 View

Can DNase1 degrade the plasmid (circular) DNA?

I had a sample of plasmid extracted from e.coli and wanted to check the amount of Host cell RNA impurity with a fluorescent dye. to do this, first of all, I treated the sample with DNase I. (NEB...

11 January 2021 2,608 3 View

How can I do y-scrambling( y-randomization) to test the developed machine learning-based model ?

Dear researchers : y-randomization is one of the special tests of machine learning approaches. I want to evaluate my developed machine learning-based models, to predict active peptides, by...

26 October 2020 1,196 2 View

How to calculate erosion in LS-DYNA?

I am modelling an impact on a Ti64 block. The impacting particles are rigid and the Johnson-Cook material has been used for the block. I am wondering how to calculate erosion; I want to analyze...

13 April 2020 4,509 2 View

Plasmid transformation protocol into Agrobacterium rhizogenes.?

I want to insert my 14kb recombinant plasmid into A.Rhizogenous, what should I do during my transformation. I transformed my plasmid with freeze/thaw transformation method, but it didn't work. I'm...

03 December 2019 960 7 View

Does anybody have a matlab code example to forecast time series with genetic programming?

I wanna forecast for future.

25 July 2018 9,687 1 View

Why is there a decreased in the XRD patterns from 5 to 20 degree for Fe3O4 ?

Fe3O4 nanoparticles were synthesized by a facile ultrasound assisted technique. FeCl3. 6H2O , FeCl2. 4H2O and NH3. XRD pattern of Fe3O4 nanoparticles. Red lines indicates the stick pattern of...

07 May 2018 3,354 3 View

Where can I get a sample of python source code for electricity price forecasting with Neural Networks?

i need data set and sample of python source code for electricity price forecasting with Neural Networks.

12 February 2018 8,440 3 View

Who can mention the possible justification for enhancing the MG dye photodegradation with increasing in weight ratio of CNT to TiO2 from 1% to 10% ?

The results of the photodegradation activity measurement demonstrated that increasing in weight ratio of MWCNT and SWCNT to TiO2 from 1% to 10% , enhanced the MG photodegradation.

13 May 2017 385 2 View

How can I measure MMP-1 protein activity or protein level from liver tissue?

Instead of checking only the mRNA level, I want to check the active protein level of MMP-1 in Liver tissue from mice. How can I do that?

03 March 2021 1,763 2 View

Can we classify HV and LV lines based on line length?

I have dataset which shows the length of power lines. I need to classify the lines based on the line length. Is there a rule to classify the High voltage (HV) and low voltage (LV) lines based on...

03 March 2021 4,116 4 View

No title

02 March 2021 3,060 3 View

How to repeat an operation on an atom selection for multiple times in PyMol?

Hi, I am trying to construct a multi-layer fibril structure from a single layer in PyMol by translating the layer along the fibril axis. For now, I am able to use the Translate command in PyMol...

02 March 2021 4,569 4 View

What analysis to choose with a large neste dataset and clearly skewed or kurtotic distributions?

Hello! I have a dataset of n=3000 nested within 8 countries with approximately 200 or 400 responses in each country. I originally planned to perform multilevel modelling with 4 dependent variables...

02 March 2021 6,865 1 View

Does Napabucasin soluble in dichloromethane and in ethanol?

I need to prepare a solution of Napabucasin (inhibitor of cancer cell stemness) in dichloromethane. The drug is expensive, so maybe somebody already tried to do it. If it is soluble, what is the...

02 March 2021 9,945 3 View

Issues with Permeabilization during Flow Cytometry?

Hello Everyone. Currently I am working to characterize macrophages in the myocardium after ischemia-reperfusion injury in rats. Due to the low total cell number isolated from rat hearts I can...

01 March 2021 3,867 3 View

Could you please recommend some good journal that accept very long revie papers (approximately 6000+ words) in neurosurgery, cancer biology ?

Could you please recommend some good journal that accept very long revie papers (approximately 6000+ words) in neurosurgery, cancer biology ?

01 March 2021 8,087 3 View

Which cell line should we use to perform biological dosimetry experiments?

We are preparing some experiments based on irradiating cells under different conditions in order to evaluate the effects in terms of DNA damage, genetic expression, etc. As our project is...

01 March 2021 3,355 3 View

IHC on mouse liver hepatocytes?

Can anyone help me choose primary antibodies for mouse liver hepatocytes and also in conjunction Cd8 cells. Also Cd3 cells. I want to look at hepatocytes and adjacent immune cells in mice with...

01 March 2021 6,953 1 View