I want to design an aptamer for morphine by in sillico method and i need some basic sequence but i can not find them. if you have a library or know some article that can help me , please introduce me. thanks
E-AB sensors, or electrochemical aptamer-based sensors, are a flexible type of sensing platform that can identify targets in complicated matrices quickly and reliably. But these sensors' low sensitivity has made it difficult for them to go from proof-of-concept to commercial goods. In order to bind targets and then fold for signal transduction, surface-bound aptamers need to be appropriately spaced apart. We postulated that conventionally produced electrodes produce sensing surfaces with only a portion of aptamers suitably positioned to actively respond to the target. Alternatively, we introduced a new method for immobilising aptamers that promotes microscale spacing between aptamers for the best possible target binding, folding, and signal transduction.
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