I am interested in the effect of different nucleases on G-quadruplex DNA.
I see examples in the literature where exonucleases or endonucleases release G-rich sequence which consequently form G-quadruplex.
However, other reported G-quadruplex-based technologies rely on S1 nuclease or DNAse 1 to cleave the formed G-quadruplex.
So, what trend in these different nucleases that would correlate with the ability to cleave G-quadruplex ?
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3655473/
https://www.pnas.org/content/98/22/12444
https://academic.oup.com/nar/article/45/21/12069/4259770
https://pubs.rsc.org/en/content/articlelanding/2015/ra/c5ra20773h#!divAbstract
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3655473/
https://www.pnas.org/content/98/22/12444
https://academic.oup.com/nar/article/45/21/12069/4259770
https://pubs.rsc.org/en/content/articlelanding/2015/ra/c5ra20773h#!divAbstract
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