Good day all, I am about starting an experiment, in which I have to induce colon cancer.
(1). Please can anyone tell me the best model to use among these; Methylazoxymethanol (MAM), 1,2-dimethylhydrazine (DMH), and azoxymethane (AOM). And also, how long will each of these agent take to induce colon cancer in rats.
(2). Can 1,2-dimethylhydrazine and azoxymethane be combined?
(3). What is the best age to induce colon cancer in rats for both sexes?
I would be grateful if anyone can help.
Thanks in advance