Whether higher PD-L1 expression is good for tumor cell itself or not?

More Fengshuang Yi's questions See All

How to improve my plaque assay for influenza virus?

I used MDCK cells for my plaque assay for influenza virus and seeded 950,000cells/well in 6-well two days before infection. The virus was diluted in FBS-free MEM with 0.5ug/ml TPCK-trypsin. Here...

11 July 2024 5,669 5 View

Why the lateral resolution of OLS5100 (Olympus) can be down to 120 nm?

The laser confocal system of OLS5100 (Olympus) can reach a lateral resolution of 120 nm, that is far beyond the diffraction limitation. Though the numerical aperture of its system is 0.95, the...

15 May 2024 1,458 3 View

Why does the EPR spectrum of MnO2 powder exhibit such wide peaks?

As known, the spin exchange coupled Mn4+ leads to a narrowd singal, at ca. g=2.006 with the line width about 500 gauss. Why the birnessite MnO2 dispalys such wide spectrum? Is any other exchange...

23 April 2024 6,351 3 View

What is the standard electrode potential of the silver wire reference electrode?

The silver wire has been used as a reference in an organic electrolyte in many artcles. What is the standard electrode potential of the silver wire reference electrode and how to calibrate its...

14 April 2024 8,052 3 View

Iso 29134 pdf?

I'm just looking for iso 29134 pdf, does anybody have any idea where I can download it for free?

08 April 2024 6,507 0 View

What techniques can enhance the inference performance of DNN and be used in edge computing?

Edge computing is a decentralized computing infrastructure that brings computing power closer to the data source, reducing latency and improving efficiency. Traditionally, computing tasks were...

19 March 2024 1,229 0 View

How to sterilize materials coated on PP in situations where high temperature and UV cannot be used?

How to sterilize a polymer grafted with a photoinitiator before cell culture?

23 January 2024 9,548 2 View

What potential by-products may occur in the EDC/NHS reaction?

I want to use carboxymethyl cellulose for an EDC/NHS reaction to attach amine-functionalized small molecules. Initially, I used an EDC:NHS ratio of 1:1, but the grafting efficiency was low. Later,...

11 January 2024 6,873 1 View

Why does the LSV curve show a linear decrease in current density at the end ?

When the LSV test is conducted with the prepared material, the image of linear decline will appear at last, but this problem will not occur when I change to other materials (such as new foam...

04 January 2024 9,718 5 View

SAP2000 V20 Pushover cannot converge, how to resolve?

I have no issues with my plastic hinge settings, and it converges well in V14. However, when opening the file in V20, it fails to converge. How should I address this? I have set the hinge...

19 December 2023 4,911 4 View

Why activated CAR-Jurkat cell could not kill targets?

Previously when I co-coluture anti-CD19(FMC63) CAR-Jurkat with Raji with E:T=5:1, Jurkat can eliminate Raji in 24h. However, when I test another CAR construct, although I can dectect totally CD69...

06 August 2024 641 2 View

Does anyone know the scoring and interpretation for Psychological Birth Order Inventory (PBOI) of White Campbell?

Hi, I am currently a upcoming 4th year student who is need of your help as I couldn't find any accessible file for the manual scoring and interpretation for the PBOI - White Campbell. My group and...

23 July 2024 2,269 1 View

What role does the gut microbiome play in immune system modulation and disease susceptibility?

Only Probiotics Related

22 July 2024 6,454 0 View

What is the suitable solvent of MIL-100 for chemotherapy?

I synthesised a nanocarrier by conjugation MOF (MIL-100) with folic acid for use in chemotherapy but the samples didn't dissolve completely in aqueous solution or DMSO. Instead, they only...

19 July 2024 8,522 0 View

You have mentioned as a co-author of one publicaitron?

You have mentioned as a co-author of one publication, but it is not exactly a publication , it is an abstract submitted to: Congresso Brasileiro de Hematologia, Hemoterapia e Terapia Celular -...

17 July 2024 4,035 15 View

What is the suitable solvent of MIL-100 for chemotherapy?

I synthesised a nanocarrier by conjugation MOF (MIL-100) with folic acid for use in chemotherapy but the samples didn't dissolve completely in aqueous solution or DMSO. Instead, they only...

15 July 2024 2,414 1 View

How do the complex dynamics of the oral microbiome interact with the host immune system affect periodontal disease development and treatment response?

This research question explores the complex dynamics of interactions between the oral microbiome and the host immune system, particularly in the development and treatment response of periodontal...

09 July 2024 7,922 1 View

The complex interactions between oral microbiota and oral mucosal immunoregulation: implications for oral health and disease development?

This research question explores the complex interactions between oral microbes and oral mucosal immune regulation. The diversity and function of oral microbes have important impacts on oral health...

09 July 2024 7,883 0 View

What is the best approach to culture a mixed immune cell population for at least 48h?

I want to isolate and culture all immune cells from the adipose tissue to isolate EVs. What is the best approach to make sure all cells survive for at least 48h?

03 July 2024 6,501 1 View

Recent understanding of the interplay between play and dementia?

Hi Everyone, I did some studies on the roles of gamification in cooperative behavior in learning and I want to extend my focus to the roles of playfulness (gaming or gamification) on aging and...

02 July 2024 2,079 0 View

Fengshuang Yi

Thanks for your answer.

Is there any special cases that tumor cells overexpressed PD-L1 is more sensitive to host immune defense?

Thank you again.@Jiang Kunpeng

Goodwin G. Jinesh

PD-L1 expression with VEGFR2, CD24 and E-cadherin forms rapid tumors because it can evade immune system and promote stemness. Here is some info on that

Article Surface PD-L1, E-cadherin, CD24, and VEGFR2 as markers of ep...