Are the comorbidities an important impact factor ? And if yes, a correct therapy of comorbidities can reduce and/or remove the impact of vitamin D on cognitive performance ?
Since Alzheimer disease is also knows as DM type 3 or central DM, maybe this article might help since it deals with DM and vit D relation.
Vit D is also an important immunomodulator, therefore it surely has an effect on the inflammatory component of neurodegeneration (presuming it being the main cause of lower cognitive performance). So searching for vit D and relations to microglia/astrocytes might also bring something.
Hope it helps,
Karlo
Article Vitamin D and pancreas: the role of sunshine vitamin in the ...
To Karlo Toljan : I have read the article you have proposed. It's interesting but it does not add nobody of original and nobody regarding the relationship between vitamina D and cognitive function.......
Is Alzheimer a central DM ? I don't known. I don't think so.