What is the mode of action of sanglifehrin A?

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Can someone suggest a protocol to grow cancer stem cells?

I am planning to grow Oral Squamous Cell Carcinoma cells in our lab. Can someone suggest a good protocol for this? Thank you

09 August 2023 7,611 2 View

What are the reasons to show the VWD detector as offline in HPLC machine?

There is a problem in our HPLC (Agilent InfinityLab LC Series, 1260 Infinity II Quaternary System) detector (Variable Wavelength Detector G7114A). It is not subjected to the auto configuration and...

26 January 2023 3,032 3 View

Can anyone suggest a trick to get the NO assay standard curve properly?

Hi, I am trying to plot the standard curve for NO scavenging assay with Ascorbic assay. I need this to test the NO scavenging ability of the plant extracts I have prepared. But the results are so...

13 September 2020 1,313 1 View

What can I do if my freeze dried plant extracts wouldn't dissolve in d. water?

Hi, I have prepared freeze-dried plant extracts. Now I want to run antioxidant assays on these plant extracts. But few powders do not dissolve in distilled water. What can I do now? Thank you in...

10 September 2020 9,083 8 View

Has anyone used the microplate reader for DPPH assay?

I have used the microplate reader for DPPH assay. I didn't have the 517 filter. So instead I used 540 filter. I received negative values for results. Could this be because I used a different filter?

21 July 2020 3,066 7 View

What are the software/tools available for SEM image analysis of bacterial biofilms?

Dear Researchers: Greetings! I am interested in learning electron microscopy image analysis of bacterial biofilms, mainly using open-source software. I have been using basic functions and tool...

28 May 2020 5,732 4 View

What does it mean when "SAM lines do not contain at least 11 tab- delimited fields in Galaxy?

I have sequenced my bacterial RNA samples using Illumina Hiseq and have good quality data. I mapped the reads to the reference genome using " Map with BWA-MEM " tool in galaxy. When I try to...

18 November 2019 9,052 0 View

How do I find a desiccant coat for enthalpy wheel?

We are working on research about the rotary thermal wheels. So we need to find some desiccant coat which can be coated on the Aluminium sheets.

21 August 2019 5,776 0 View

What are the physical characteristic of a drought and how to account socioeconomic vulnerability when delineating a hazard map on regional scale?

This is a random question that I have been thinking of. Just by considering the magnitude or the physical characteristics of a hazard, we cannot say that a particular area is vulnerable to it. If...

21 July 2018 5,342 3 View

Would you be interested in my sending to Research Gate my bibliography? Many entries, e.g. origin of Aids, published in newspapers are accessible?

Would you be interested in receiving my bibliography of publications? Some publications, such as one on the origin of Aids, are as carefully prepared as in a peer reviewed journal but were offered...

04 June 2018 3,753 3 View

Tissue homogenization in mouse with FastPrep-24™ 5G - is the D matrix system useful?

I need to lyse and homogenise mouse tissues. So far I have experimented with liver and lung tissue, using matrix D. The liver was completely lysed with 6 repetitions of the standard program, but...

31 July 2024 9,186 0 View

What it is, that we do not know about the possible Social Impact of the AI on Society. Education, Human Computer Interaction and the Global Economy?

As with most changes in life, there will be positive and negative impacts on society as artificial intelligence continues to transform the world we live in. How that will balance out is anyone’s...

20 July 2024 10,062 3 View

How can reinforcement learning algorithms be effectively applied to study decision-making processes in neuroscience?

I am interested in exploring the intersection of neuroscience and AI, particularly through reinforcement learning for understanding decision-making in the brain. I also want to integrate...

17 July 2024 1,225 0 View

How do the complex dynamics of the oral microbiome interact with the host immune system affect periodontal disease development and treatment response?

This research question explores the complex dynamics of interactions between the oral microbiome and the host immune system, particularly in the development and treatment response of periodontal...

09 July 2024 7,922 1 View

Do the parts of the body that are situated at a longer distance from the central nervous system have the least control & coordination comparatively?

What would be the effect of distance from CNC cum Heart on the structure and function of a particular part of the human body? Do short people have evolutionary advantages to control body parts in...

09 July 2024 2,052 3 View

What is the association and mechanism between bacterial diversity in the oral microenvironment and clinical manifestations of periodontal disease?

This research question explores the complex relationship between bacterial diversity in the oral microenvironment and the clinical manifestations of periodontal disease. The oral microenvironment...

09 July 2024 6,210 1 View

Are there any people using biolegend anti- mouse CCR2-BV785?

Hi, I'm working on heart flow cytometry, and I use anti-mouse CCR2-BV785 (biolegend, cat150621) for staining, 20 minutes, 4 degree. But I couldn't see any CCR2+ cells. So I'm not sure if it's...

03 July 2024 3,969 4 View

How to select drugs for repurposing?

Hello everyone, so I am searching for ways to find the method for picking the right drug for repurposing. This repurposing is for existing and new diseases. This is very important, please help.

23 June 2024 7,730 2 View

Use of agency vs. google-translation for translating non-english qualitative data?

Hi, As part of a miltilevel study examining the impact of steroid toxicity in patients with different rheumatic diseases (see here: https://vasup.ndorms.ox.ac.uk/) we collected data from the UK...

17 June 2024 4,016 4 View

Have pathomorphological studies of the lungs been performed in patients with desminopathy?

It is known that patients with desminopathy often die from pneumonia. Have pathomorphological studies of the lungs been performed in patients with desminopathy?

15 June 2024 1,355 7 View