What is the eventual fate of Long noncoding RNA (LncRNA)- microRNA (miRNA) sponge?

06 March 2018 1 6K Report

Dear fellow researchers,

Several researches in the recent time have highlighted that LncRNAs exert its function through miRNA via sponge formation. We also know that in usual case miRNA represses expression of coding gene targets via degradation or by suppressing its translation. Since, LncRNA doesn’t get translated, what is the eventual fate of the LncRNA-miRNA complex/sponge inside the cell?

Mushtak T. S. Al-Ouqaili

Dear Prabhash...

I thin the fate of these molecules is likely to be degradation, just like tRNA one.

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