What is an effect of APPJ on cancer cell treatment?

07 February 2019 1 4K Report

Discussion about its results

Hom,

While visiting Tissue Engineering Group at Technical University of Catalonia in Barcelona in 2015, I've learnt news about pioneering therapies for bone cancers. Namely, an alternative therapy was found in cold plasmas generated at atmospheric pressure. They employed an atmospheric pressure plasma jet (APPJ) to test its selectivity towards osteosarcoma cell line vs. osteoblasts & human mesenchymal stem cells. Among major findings were delayed effects are observed which lead to 100% bone cancer cell death through apoptosis, while contact of APPJ with healthy cells did not lead to any affects. Authors speculated on an important role of the reactive oxygen species and reactive nitrogen species in the gaseous plasma stage and then transmitted to the liquid phase, - all leading to treatment of metastatic bone disease with that minimally invasive approach.

Best wishes,

Ilya

Badges
Science topic

More Hom Bahadur Baniya's questions See All

Does the Covid-19 pandemic have any positive consequences on Environment??

Does the Covid-19 pandemic have any positive consequences on Environment?? if you have any opinions/evidences/data records, I am very much eager to know it, would you pls share with us?. I am also...

11 August 2020 5,987 4 View

Whats the name of this fruit?

13 October 2016 9,076 63 View

Is there any book for step to step data analysis for SPSS beginners ?

Many students frequently ask this questions. Students from under developed country have some difficulty to purchase the expensive book. Do you have any idea about the free access of such a book so...

28 December 2014 6,460 14 View

How to distinguish polymeric Molybdate and Monomeric Molybdate by IR?

I am facing problems to distinguish monomeric molybdenum compound (eg CaMoO4) from polymeric molybdenum compound (eg (NH4)6Mo7O24 or its hydrates). I am trying to distinguish using FT-IR, do...

04 December 2014 1,804 2 View

Does the NMDS score represent latent environmental variables?

Dear vegetation community and multivariate users, I liked discussions here related to selection of different ordination methods. In this connection I have a query related to using NMDS score value...

17 November 2014 1,444 1 View

Why journals use fake Digital Object Identifier (DOI) in the published article ?

I have recently encountered Fake DOI used in the published article? Is there any legal action author can do for it?

01 January 1970 7,453 10 View

What happens if your same article publishes in two journals in spite of authors awareness about ethical issues?

Dear Researcher, Recently I am in stress as my same article published in both Journals. 1. the First journal denied publishing it without paying publication charges. Then I emailed them...

01 January 1970 4,610 4 View

Why does blocking with my immunogenic peptide cause nuclear fluorescence in ICC?

Hi all, I am validating a polyclonal antibody raised against human ANT4, through WB and ICC. In most of my controls, the antibody shows very little off-target binding, but when I pre-incubate the...

03 March 2021 5,999 3 View

Does Napabucasin soluble in dichloromethane and in ethanol?

I need to prepare a solution of Napabucasin (inhibitor of cancer cell stemness) in dichloromethane. The drug is expensive, so maybe somebody already tried to do it. If it is soluble, what is the...

02 March 2021 9,945 3 View

Help request in CST microwave?

im working now on TPV solar cells and metamaterials and i realy need our help in CST microwave i have a tpv cell simulation and i want to extract particullarly the absorbtion of only the active...

02 March 2021 2,246 2 View

Could you please recommend some good journal that accept very long revie papers (approximately 6000+ words) in neurosurgery, cancer biology ?

01 March 2021 8,087 3 View

Which cell line should we use to perform biological dosimetry experiments?

We are preparing some experiments based on irradiating cells under different conditions in order to evaluate the effects in terms of DNA damage, genetic expression, etc. As our project is...

01 March 2021 3,355 3 View

Is CD44 degraded in lysosome together with hyaluronan after CD44 mediated endocytosis of hyaluronic acid?

Also when RHAMM binds hyaluronic acid, they get internalized, will RHAMM also be degraded? Or both CD44 and RHAMM will be transferred back to the cell membrane? Asking for breast cancer cell line...

01 March 2021 8,169 2 View

Dapi fluorescence protocol for colon cell lines ?

28 February 2021 2,534 2 View

Does RNAiMAX transfection reagent work in serum free medium?

I diluted siRNA and RNAiMAX in opti-MEM and added to the cells which they were in the growth medium. Is it a right way? or should I culture cells in the opti-MEM medium for a while and not in...

26 February 2021 10,041 3 View

Has anyone had luck using cell lines other than HEK 293 (such as COS1) to package lentivirus?

I am looking to package lentivirus in endothelial cells but I am opposed to using 293 cells due to personal ethics regarding the source. I have done some reading and saw that COS1, COS7, & CHO...

25 February 2021 3,030 1 View

Unknown debris sheets observed in cell culture flasks?

Hi, We culture neural progenitor cells in T175 culture flasks coated with PLO-Laminin. We have successfully grown these cells with our protocol for months. Recently, we observed large sheets...

25 February 2021 3,443 4 View