I use HFIP for dissolving hIAPP (Amylin) fibrils to make monomers. I would like to ask Which solvent could be a replacement for HFIP to dissolve amyloid fibrils?
Apart from HFIP, you can either use 2,2,2-trifluoroethanol (TFE) or dimethylsulfoxide (DMSO) for dissolving amyloid fibrils. DMSO is required in a higher amount (80%v/v). For further reading, you can go through the following articles.