Can CMOS and CCD images sensors be used as microphones?

I was thinking about Msps and Gsps image sensors in different environments. If a pair of identical image sensors - one exposed to air, gases, plasmas, or partial vacuum - and one in a good...

21 December 2020 9,747 2 View

Proper method for assessing model invariance following Confirmatory Factor Analysis (CFA) and preceding 2x2 between-subject analysis?

I have produced a good-fitting, reliable baseline model according to CFA. The model contains several factors each loaded by several categorical (ordinal) items. I ultimately intend to analyze the...

15 December 2020 1,668 4 View

Hello researchers, can anyone help me with this Structural Decomposition Analysis (SDA)?

I am using Economic Input-Output Life Cycle Assessment (EIO-LCA) model I need to decompose this equation W= P*F* L* Yc* Yg to generate 120 forms. where W is a vector of total water withdrawal...

20 November 2020 4,194 3 View

How do I better visualize protein interactions at edges of periodic box in VMD?

I have a 500 ns molecular dynamics trajectory with several proteins in a membrane. The entire system is enclosed in a periodic box. Unfortunately, my proteins are only interacting around the...

11 November 2020 6,912 3 View

Which part of the ovarian follicle in poultry can I use for RNA and protein extraction. The outer layer or the inner fluid?

Should I use the covering of the follicle or the liquid fluid for RNA and protein extraction. Which technique is easier to use

01 September 2020 3,094 3 View

If I Have one Group of Participants, is There a Statistical Analysis for this?

5 August 2020: Looking for assistance on a review of the calculation of my work on Kendall's W and Tau. This method made more logical sense in that its heavily used for survey responses. I also...

27 June 2020 5,983 4 View

How expensive are commercially available customized molecular dynamics services?

I am interested in potentially using commercially available customized HPC molecular dynamics simulations. However, I cannot find pricing information on the websites of the vendors. Could someone...

07 June 2020 9,137 3 View

What is the role of journals' reviewers? Should they be absolute judges?

- Ask questions where they are not sure/convinced about a statement/conclusion VS reject a statement/conclusion where they 'think' it is not correct? - Provide suggestions to improve a...

21 May 2020 2,624 7 View

What is the importance of social network analysis in research?

Beyond the beautiful lines or webs showing how connected an individual is, what other meaningful analysis could be done? for instance, are those directly connected the the individual more...

06 February 2020 5,574 3 View

Does EDC/NHS coupling act on primary amides or only primary amines?

I want to use a coupling reagent (possibly EDC/NHS) to link gold nanoparticles to primary amines and NOT primary amides. There are both primary amines and primary amides in my sample, but I want...

16 January 2020 7,378 4 View

Can we classify HV and LV lines based on line length?

I have dataset which shows the length of power lines. I need to classify the lines based on the line length. Is there a rule to classify the High voltage (HV) and low voltage (LV) lines based on...

03 March 2021 4,116 4 View

No title

02 March 2021 3,060 3 View

Issues with Permeabilization during Flow Cytometry?

Hello Everyone. Currently I am working to characterize macrophages in the myocardium after ischemia-reperfusion injury in rats. Due to the low total cell number isolated from rat hearts I can...

01 March 2021 3,867 3 View

Which cell line should we use to perform biological dosimetry experiments?

We are preparing some experiments based on irradiating cells under different conditions in order to evaluate the effects in terms of DNA damage, genetic expression, etc. As our project is...

01 March 2021 3,355 3 View

Is it possible for two human neuronal cell lines to have different gene sequence for the same protein?

I am looking at the ATP1A2 (Sodium/Potassium ATPase alpha subunit 2) in two human neuronal cell lines. Expression levels of this protein seems to be almost equal when detected by one antibody....

01 March 2021 3,607 3 View

Is CD44 degraded in lysosome together with hyaluronan after CD44 mediated endocytosis of hyaluronic acid?

Also when RHAMM binds hyaluronic acid, they get internalized, will RHAMM also be degraded? Or both CD44 and RHAMM will be transferred back to the cell membrane? Asking for breast cancer cell line...

01 March 2021 8,169 2 View

Do you need the CMV enhancer before the CMV promotor for a proper function of CMV on the gene that follows?

I'm a student and I have to produce a cell line with a knockin for the NRF2 gene with GFP. I have to put a promotor in front of the GFP because the gene will be too far away from the promotor of...

28 February 2021 7,127 2 View

What could be some reasons why unstimulated monocytes are getting activated?

Im doing PBMC isolation -> CD14+ enrichment using magnetic beads -> stimulation setup. My negative control is just cells in cRPMI but they seem to get activated over and over again.

28 February 2021 7,883 3 View

No title

28 February 2021 9,936 2 View

Has anyone had luck using cell lines other than HEK 293 (such as COS1) to package lentivirus?

I am looking to package lentivirus in endothelial cells but I am opposed to using 293 cells due to personal ethics regarding the source. I have done some reading and saw that COS1, COS7, & CHO...

25 February 2021 3,030 1 View