Try using Phyre2

Use SwissModel

thanks for your suggestion but i have use phyre2 and swiss model but the result is not good, because IRS-I protein didn't have homolog in PDB..

Try Raptor X server

There are many servers that allow protein modelling, some of which are mentioned above. But still using the Modeller is the best option for modelling a protein. Modeller now also has a GUI interface, so u can easily model a protein using modeller . hope this helps. Best of luck :)

Use Protein model portal . The goal of the Protein Model Portal (PMP) is to provide a single portal which gives access to the various models like ModBase,SWISS-MODEL, I-tasser etc

There are various softwares which are helpful to protein modelling

1.Modeller and swiss-model are free to use and also provide authorization to publish.

2.While MOE, Discovery studio and schrondinger are paid ones.

As you mentioned that your protein dosen't have a homolog in PDB, so you may face difficulty in homology modelling. You may attempt threading approach or ab initio predictions for protein modelling. All the best. Be prepared that you may not get a high scoring model with very good predictions.

Dear,

Ratih

this is the list protein modeling software that you can use it

http://en.wikipedia.org/wiki/List_of_protein_structure_prediction_software

if homology modeling and threading approach can give the result. build your own protein with de novo approach (on the list).

you can use web-server or standalone program.

I suggest you to try this one.

http://boinc.bakerlab.org/rosetta/

good luck