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09 October 2014 5,593 1 View

Is there a website to assess the aggregation of peptides and proteins?

What is the most relevant website to predict the aggregation?

02 March 2014 5,793 1 View

Could someone suggest a website which shows how to calculate the electronic properties of unnatural amino acids?

02 March 2014 3,704 1 View

Is there a website to check if the signaling of GPCR is impacted after mutations?

I would like to test how multiple mutations impact the signaling of GPCR.

02 March 2014 4,512 5 View

Any example of peptides or proteins mutations with regards to Half life?

I would like some learning data sets (WT + a lot of mutants) in relation to half life.

02 March 2014 5,158 0 View

Aggregation of protein and peptides: Is there any example of WT + a lot of mutations in relation to aggregation?

I would like some learning data sets (WT + mutants and aggregation values for each) to assess the robustness of an algorithm.

02 March 2014 9,000 1 View

Is there a website to assess the thermostability of peptides and proteins?

What is the most relevant website to predict the thermostability of peptides?

02 March 2014 7,970 3 View

What are the amino acids residues involved at the active site of Malate Thiokinase?

Malate thiokinase active site residues

11 December 2013 4,061 4 View

What it the best algorithm to predict half life of a peptide or a protein?

What are the best mutations to extend half life of a peptide or a protein?

11 December 2013 9,465 3 View

What is the difference between genotype and haplotype data in the ped format?

Hi everybody In the ped format for genotype, alleles of any SNP are represented by two columns (one for each allele, separated by a space). Is a column sufficient for the haplotype to...

27 February 2021 1,965 1 View

Are there any databases for gene co-expression or expression pattern clustering?

I am currently working on gene clustering based on co-expression pattern in mouse brain. The problem is I do not have some solid way to test my result. Are there any suggestions for databases...

22 February 2021 4,374 3 View

Useful architecture for bioinformatics?

Hi Dear researchers In ensemble-based architectural design Which algorithms are more useful for classification? What is the difference between parallel and ensemble architecture? Thanks I am...

08 February 2021 2,727 5 View

Electron density difference maps(Fo-Fc): what is the meaning of negative densities (red blobs)?

Dear community, As far as I understand, negative density features point at stuff that is in the model, but not supported by experimental data. However, in many cases (e.g. attached image), when...

06 February 2021 2,847 2 View

Qiime2- No reads passed the filter. How to set the trunc value?

Hi, I am working on some 16S sequencing data, and seems some of them are low quality. I am not sure how to set the trunc value in dada2. qiime dada2 denoise-paired \ --i-demultiplexed-seqs...

30 January 2021 6,213 3 View

Which software to use to statistically analyze Telomere Length_TRF_Southern Blot?

I am trying to measure telomere length in an ant species using the TRF method, which is a Southern blot technique. Currently, I am struggling with analyzing the images and would appreciate any...

29 January 2021 604 3 View

MHC Rabbit Genome Annotation? Domain annotation of each MHC Rabbit Gene?

I want to find a database(s) or a method where I can find and bulk download all the rabbit MHC genes and domain annotation. In humans using Ensembl, all MHC genes have names and domains but in...

28 January 2021 7,722 2 View

Best tool to build missing residues, minimize and validate a ligand model?

I am working on a ligand that is co-crystalized to parotein, but the ligand is missing some residues that makes it appear as if it was separated into two ligands! what I need is to connect them...

23 January 2021 3,975 7 View

What's the role of bioinformatics in poultry science?

bioinformatics has a big importance in human science and lots are seeking to study that field, so it attracts me to know it's relation with poultry science and how we can benefit from it in...

20 January 2021 6,963 3 View

How can I get the chromosomal location of a list of genes?

I'm looking for a bioinformatics website to get the chromosomal location of a radish gene id list, but in one shot instead of doing it gene by gene. Is there a way to do this? Thanks

17 January 2021 8,810 3 View