What it the best algorithm to predict half life of a peptide or a protein?

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What are the Tm for the different Staphylococcal enterotoxins?

What is the ranking of Staphylococcal enterotoxins in terms of Thermal stability (Tm °C)?

09 October 2014 5,664 1 View

Is there a website to assess the aggregation of peptides and proteins?

What is the most relevant website to predict the aggregation?

02 March 2014 5,858 1 View

Any example of peptides or proteins mutations with regards to Half life?

I would like some learning data sets (WT + a lot of mutants) in relation to half life.

02 March 2014 5,267 0 View

Could someone suggest a website which shows how to calculate the electronic properties of unnatural amino acids?

I need to calculate the relevant descriptor (electrostatic potential, hydrophobicity…) of artificial amino acids.

02 March 2014 3,759 1 View

Is there a website to check if the signaling of GPCR is impacted after mutations?

I would like to test how multiple mutations impact the signaling of GPCR.

02 March 2014 4,606 5 View

Prediction of half life for peptides and proteins: is there a website to assess the half life?

What website could assess the half life of peptides and proteins?

02 March 2014 8,967 1 View

Aggregation of protein and peptides: Is there any example of WT + a lot of mutations in relation to aggregation?

I would like some learning data sets (WT + mutants and aggregation values for each) to assess the robustness of an algorithm.

02 March 2014 9,060 1 View

Is there a website to assess the thermostability of peptides and proteins?

What is the most relevant website to predict the thermostability of peptides?

02 March 2014 8,041 3 View

What are the amino acids residues involved at the active site of Malate Thiokinase?

Malate thiokinase active site residues

11 December 2013 4,128 4 View

GC-MS retention index prediticon?

Hello experts, Does anyone know any free software about retention index prediction ?

08 August 2024 7,403 2 View

How to increase simulation box size?

We intend to study the interaction between peptides and polymer (like PP, PE and PS) through MD simulations using Martini force fields ( Martini 2 for PP and Martini 3 for PE, PS). We have...

08 August 2024 4,842 0 View

Unusual intensity drop in some sections of chromatograms in DDA?

Hi, we have measured tryptic peptides using both DDA and DIA method on QExactive. In DDA replicates i saw unusual intensity drops occurring at the same sections of chromatograms in DDA replicates...

07 August 2024 3,218 4 View

How to analyze multiple phosphorilation sites?

Hello, I am currently analyzing some phosphoproteomics data, but I have peptides with multiple phosphorylation sites or phosphorylations together with carbamidomethylation or oxidation. How can I...

04 August 2024 8,432 3 View

Can anyone provide me with molecular docking softwares/ websites?

Molecular docking software/ websites?

02 August 2024 8,704 7 View

Recovery rate after peptide desalting using Sep-pack C18 1 cc Vac Cartridge?

Recently I'm trying to use Sep-pack C18 1 cc Vac Cartridge (Waters: SKU: WAT054955) to desalt digested peptides. However, the recovery rate is usually 40-60%. What is the normal recovery rate?

31 July 2024 6,544 11 View

I am working on my Master's thesis on the biogeography of the genus Ruagea and I would like to ask, could someone help me to check whether my result?

I created a file with my outgroup and ingroup species using Beauti, ran it in BEAST, viewed it in Tracer, and then used TreeAnnotator to create a file that I imported into RASP. Could someone...

28 July 2024 2,979 1 View

Which software tools are best for enhancing diagnostic accuracy in chest X-ray imaging using image reconstruction and neural networks?

I am reaching out to seek your valuable advice and recommendations regarding the best software tools to use for this research. Specifically, I am looking for software with a user-friendly...

22 July 2024 3,794 1 View

How to test multivariate outlier in STATA?

Hey all, I need help testing for multivariate outliers using STATA for my master thesis. The literature recommends the Minimum Covariance Determinant (MCD) (Verardi & Dehon, 2010). I found the...

22 July 2024 8,821 2 View

MDCI module in Orca software?

Dear Researchers, My question is associated with the "MDCI" method in Orca. Please let me clarify my question using a simple example: Suppose we are going to perform CBS extrapolation using "!...

21 July 2024 1,632 0 View