7 Questions 16 Answers 0 Followers
Questions related from Marco Bolis
I have 40 cancer cell lines that were treated with a specific drug, and drug response was quantified with an appropriate numeric score ranging form 0 to 1. I have gene expression data (untreated)...
04 April 2014 7,085 2 View
I determined the sensitivity of 40 breast cancer cell lines to a previously untested chemical compound. For each of the cell lines (before treatment) I have multiple Omics data: Gene Expression,...
03 March 2014 391 9 View
I could find some experiments searching for "Proteomic profiling by array" in GEO and array-express, but I'm wondering if there is more outside or if that is all for now?
03 March 2014 4,195 7 View
I'm working on an RNASeq batch of data and I'm interested in discriminating gene isoforms. I performed the analysis using the classic tuxedo suite bowtie+tophat+cufflinks. I've seen many papers...
03 March 2014 8,821 5 View
I have access to a computer cluster made of 44 nodes. Each node has 12 cores and 48 GB ram. The main problem is that jobs have a maximum walltime of 6h then they get killed, but I can use as many...
03 March 2014 7,348 7 View
I created my first randomForest model (regression) in order to predict sensitivity to a particular drug in breast cancer cell lines. Total features were 35000 and I used default mtry for...
02 February 2014 3,971 3 View
I have several gene-expression datasets and would like to perform a meta-analysis by combining p-values using Fisher's method. I used to perform this using p-values derived from differential...
10 October 2013 2,487 2 View