Dear colleagues, we need to induce a melanoma-derived tumor in the monkeys. Whereas, murine melanoma cell lines are available, i can't find any similar monkey cell line. Is it possible and reasonable to induce tumors in monkeys by using human cell lines?
As to the first part of your question: the answer is no: there are currently about 1200 non-human primates cell lines in the Cellosaurus and none of them is from a melanoma. This is not surprising as this is a very rare disease in monkey. See for example:
https://pubmed.ncbi.nlm.nih.gov/19667361
Where it is stated that searches in a number of bibliographical databases "did not reveal any published report of uveal melanoma in a nonhuman primate."
and
https://pubmed.ncbi.nlm.nih.gov/19793176/
Where it is said that "To our knowledge, this is the first documented case of melanoma in a cynomolgus monkey."
So its unlikley someone has had the opportunity to establish a non-human primate melanoma cell lines.
Best
Amos
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