Hello,
I am working with exosomes and wanted to see if there is any way to collect the DNA during RNA isolation. I use the miRCURY kit to isolate the RNA from exosomes that also preserves miRNA. But my PI advised me that it's possible to obtain DNA from the same workflow following the addition of 100% ethanol step along with the lysate into the column. Could anyone suggest if this approach would work fine to obtain reasonable amounts of exosomal DNA from serum?