Alzheimer's disease - Amyloid-beta plaques - available drug?

Dear all, Is there any available FDA-approved drug that can disable the formation of amyloid plaques or attenuate the progression of Alzheimer's disease once plaque formation is initiated...

30 December 2020 9,505 1 View

What is the best lubricant and dispersant for SiC abrasive particles ?

I am examining laboratory cases about ZnO Based ceramic Lapping with SiC,Al2O3,CeO2 and SiO2 abrasive particles. but i have no experience about modifying SiC slurry lapping. Also,i use of double...

13 December 2020 4,327 4 View

Which type of resistor is used for high frequency applications?

This project is related to transient states. I want to study the behaviour of a circuit (like a current source) by suddenly increasing the resistance from one value (5 ohms) to another (10...

07 September 2020 6,665 28 View

How can I compare the current ADHD-RS total score with the score related to 6 months before now?

Dear all, I want to analayze the inattentiveness level in ADHD patients and compare the current score with the score of 6 months before now. I do not have any score of inattentiveness level of 6...

05 September 2020 5,094 3 View

Do you know any special research unit in Neuroscience field where I can spend a semester as an internship or a free mover student??

Hi dear readers, I am really interested in Neuroscience and Neuropsychiatry, and am really eager to do more research in these fields. Since I live in a developing country and don't have enough...

18 August 2020 8,044 3 View

How to find equivalent static loading of dynamic events in Abaqus?

To find equivalent static loading of dynamic events, displacement vector of the dynamic analysis could be used as attached picture. To use this method in Abaqus, how we could export the...

15 August 2020 8,287 5 View

How to reduce extruder vibration?

I'm trying to reduce a 3d printer extruder vibration. When the extruder starts to move, vibrates that decrease printing quality. How can I reduce the vibration? I need a procedure to solve the...

05 August 2020 4,296 2 View

Is my understaning of feature extraction process is right??

I'm working on an activity recognition project using smartphone sensors data and I want to implement feature extraction phase. Assume the frequency of data collection is 20Hz and the sliding...

01 June 2020 8,580 9 View

Is it possible to damage the solar panel by injecting Impulse voltage?

09 April 2020 4,525 2 View

How to use of deep network designer toolbox in matlab software for training a model ?

I have an input data set as a 5x100 matrix. 5 indicates the number of variables and 100 indicates the number of samples. I also have an target data set as a 1x100 matrix, which is continuous...

09 April 2020 7,103 4 View

Does the pressure(-600 mmHg) affects pH?

When I conducted the degassing experiment using decompression under anaerobic condition(and I used ferrous based chelating agent), the oxidized ferric were observerd. So, could you tell me the...

03 March 2021 4,892 5 View

What is the production process of CaFe ferroalloys?

I looking for ferro calcium production process

03 March 2021 1,755 4 View

How do I increase the yield of my PCR product?

Hello, We would like to increase the yield of our PCR product. We are running a series of PCR reactions that is targeting ~1.1kb sequence. We begin each reaction with ~400pg of template DNA...

02 March 2021 4,029 3 View

What solvent can I used for Paal Knorr reaction between 6-amino hexanoic acid and 2.5 hexanedione?

I am try to make the Paal Knorr reaction between 2.5 hexnedione and 6-amino hexanoic acid, my problem is type of solvent to use, because 6-hexaminohexanoic acid is soluble in water but I am not...

02 March 2021 4,443 2 View

Precipitate after adding laemmli buffer to protein solution containing Potassium Acetate?

Hi, I am running a size exclusion chromatography experiment with a buffer containing Potassium Acetate as a salt. I analyse these fractions through SDS-PAGE. After boiling my SEC fractions in...

01 March 2021 2,622 3 View

Is CD44 degraded in lysosome together with hyaluronan after CD44 mediated endocytosis of hyaluronic acid?

Also when RHAMM binds hyaluronic acid, they get internalized, will RHAMM also be degraded? Or both CD44 and RHAMM will be transferred back to the cell membrane? Asking for breast cancer cell line...

01 March 2021 8,169 2 View

I want to performe MALDI-TOF MS for bacterial identification, I would appreciate it if anyone can tell me the matrix solution preparation protocol ?

based on what I've studied on multiple papers, for peptide and protein identification Alpha-cyano-4-hydroxycinnamic acid (CHCA) is an appropriate matrix to use, I also know that the CHCA powder...

26 February 2021 6,799 3 View

Which database would give me this list of chemical components?

Dear colleagues: I would like to know if anyone knows of a database that gives me the parameters pH, K, K, Mg, P, C, N, Zn, Cu, Ni and Cd of common foods. I find a lot of information of proteins,...

26 February 2021 5,525 3 View

Why is NH4OH added in heavy metals limit test?

The limit test I'm referring to is USP method II. In this procedure you need to dropwise add 6N of NH4OH to the sample until it the pH is alkali. After that you need to dilute and add HOAc until...

23 February 2021 2,049 3 View

Can I use acetic acid with an ELITE WAX Perkin Elmer column for Gas Chromatography?

Hi! I would want to know if I can use acetic acid with an ELITE WAX Perkin Elmer column for Gas Chromatography. This column has a polyethylene glycol phase, but I can't find the manual to check...

22 February 2021 730 2 View