After excision and biopsy of extranodal (isolated) lymphomas of the upper airway: what is next? What forms of chemotherapy are given and for how long? What is the mean follow-up period?
Dear Dr. Askar! Treatment of lymphomas highly depend of it subtype. Can you clarify the type of lymphoma (MALT-lymphoma, follicular etc).
Regards, N Zhukov
Dear Dr Zhukov,
Let us begin with B-cell lymphoma, and T-cell lymphoma, in a 50-60 years old.
Dear Dr. Khaleque, it's hard to believe, that SOLITARY EXTRANODAL lymphoma is T-cell lymphoma/leukemia requiring ALL-like treatment. This type of lymphomas is very aggressive, so localized stage is very-very unlikely! The precise morphological examination is crucial for the treatment decision. But... If it's impossible technically (hospital haven't required morphology lab) CHOP-like chemotherapy is more 'universal' treatment.
One important point in treatment policy in extranodal NHL is intrathecal therapy that not be forgotten
Dear Colleagues,
I want to know your institution regimen, in case of extranodal lymphomas (B or T-cell; although i personally agree with Dr Zhukov assumption, as B-cell is more commonly encountered),
please mention your types and periods of medications;
Also, do you like to prescribe a therapeutic course of radiotherapy in those cases?
Dear Dr Payandeh;
please clarify your comment, as regard indications, type of medication, dose, and duration.
Dear Dr Askar you must to know subtype of lymphoma et first, and you must performed all staging with boum merrow biopsy too. After that you decided what to do.
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