The LOD scores of 3.0 were used to detect and declare the presence of a putative QTL (Zhang et al., 2017). Furthermore, a QTL with an LOD value >5.0 and a phenotypic variance contribution >10% (on average) was defined as the major QTL; a QTL with an LOD value >3.0 but
Dear Stephan Schie , very good explanation. If you have solid examples, one each, for pleiotropic expressions, please share. The two likely scenarios are 1) many genes operating one after the other and 2) genes acting simultaneously but parallely finally converging in to one expression. I am sure the straight chain one is too simplistic but if few genes are involved it may be possible. Thanks
I am sorry but I dont have any examples. I just googled it, since I have never heard about that before. As I dont work in science anymore, but in industry, I dont calculate any QTLs anymore.
Pleiotropy is always an underestimated phenomenon. Likewise, gene interaction. The balance God has achieved in a life form is complex. Hard work always pleases him and that is the reason we get results in a research endeavour. I have experienced this as a plant breeder.