Suppose you have built a network based on gene expression or protein interaction. How can I compare the current network with that from KEGG? Is there any statistics or software?
If you want to do compare the topological structure of the networks you can use Netnanalyzer or centiscape plugin of Cytoscape. Kindly find the link to the article showing the comparison.
Article The protein–protein interaction network of the human Sirtuin family