How can I compare two (or more) networks?

Suppose you have built a network based on gene expression or protein interaction. How can I compare the current network with that from KEGG? Is there any statistics or software? Best regards,

31 December 2014 115 3 View

How can I methylate or demethylate certain loci in human cell lines?

31 December 2014 2,586 3 View

Is there any recommended pipeline or procedure for Illumina Methylation 450K microarray analysis?

Is there any recommended pipeline or procedure for Illumina methylation 450K array analysis. and What we can do as a analyst when we obtain some methylation 450K array for some paired case and...

31 December 2014 4,793 9 View

How can I get the secondary structure of pre-microRNA?

31 December 2014 3,834 4 View

Do you know of any R packages for analysis of case-control studies in genetic epidemiology?

As we know, case-control based genetic epidemiological studies has played important role in susceptibility factor identification. Now, would you mind suggesting some helpful R packages to do SNP...

31 December 2014 701 3 View

How can I do sample size estimation for GWAS study?

Usually, when we conducted candidate gene based association study, we need to estimate the sample size and the power. Is it necessary to do it when we conduct GWAS study? If yes, is there any...

31 December 2014 7,577 2 View

Is there any article on Relationship between DNA Methylation and Human Evolution?

DNA methylation was involved in the evolution of duplicate genes, gene expression, miRNA network stability. Question, Is there any great article to discuss The Relationship between DNA Methylation...

31 December 2014 3,815 1 View

Powerful pipeline for miRNA-seq analysis?

Which pipeline is a suitable one for miRNA-seq analysis? CAP-miRSeq, miRNAkey or others?

31 December 2014 114 4 View

How can I get the KEGG Pathway Network in mathematical form?

We can get the elements (genes) of each pathway of KEGG from KEGG website of UCSC database. However, how can we get the network relationship in the form of network for KEGG pathway as the...

31 December 2014 2,665 3 View

Can we perform Extension of Methylation of the 450K microarray?

As we know that Methylation 27K and 450K has been widely used in genome-wide DNA methylation detection. However, they are still very small compared with whole genome CpG sites. Is there any larger...

31 December 2014 6,243 0 View

error in running a model in Abaqus

Excessive rotation of nodes in node set ErrNodeExcessRotation-Step1

17 August 2021 0 0 View

error in modelling model in Abaqus

Excessive rotation of nodes in node set ErrNodeExcessRotation-Step1

17 August 2021 0 0 View

MD MOE RMSD

How to calculate the RMSD values for a MD simulation using MOE?

07 August 2021 0 0 View

MD MOE RMSD

How to calculate the RMSD values for a MD simulation using MOE?

07 August 2021 0 0 View

MGL tools

20 June 2021 0 0 View

fatal error

When I tried to energy minimization my system, I got fatal error as below. Fatal error: Atomtype opls_116 not found Although I've already added this line: ; include water #include "oplsaa.ff/spc.itp" to [molecultype] directive in my topology.

16 June 2021 0 0 View

fatal error

When I tried to energy minimization my system, I got fatal error as below. Fatal error: Atomtype opls_116 not found Although I've already added this line: ; include water #include "oplsaa.ff/spc.itp" to [molecultype] directive in my topology.

16 June 2021 0 0 View

fatal error

When I tried to energy minimization my system, I got fatal error as below. Fatal error: Atomtype opls_116 not found Although I've already added this line: ; include water #include "oplsaa.ff/spc.itp" to [molecultype] directive in my topology.

16 June 2021 0 0 View

fatal error

When I tried to energy minimization my system, I got fatal error as below. Fatal error: Atomtype opls_116 not found Although I've already added this line: ; include water #include "oplsaa.ff/spc.itp" to [molecultype] directive in my topology.

16 June 2021 0 0 View

i have some problem with chtMultiRegionSimpleFoam

--> FOAM FATAL ERROR: Maximum number of iterations exceeded From function Foam::scalar Foam::species::thermo::T(Foam::scalar, Foam::scalar, Foam::scalar, Foam::scalar (Foam::species::thermo::*)(Foam::scalar, Foam::scalar) const, Foam::scalar (Foam::species::thermo::*)(Foam::scalar, Foam::scalar) const, Foam::scalar (Foam::species::thermo::*)(Foam::scalar) const) const [with Thermo = Foam::hConstThermo >; Type = Foam::sensibleEnthalpy; Foam::scalar = double; Foam::species::thermo = Foam::species::thermo >, Foam::sensibleEnthalpy>] in file /home/ubuntu/OpenFOAM/OpenFOAM-4.1/src/thermophysicalModels/specie/lnInclude/thermoI.H at line 66. FOAM aborting #0 Foam::error::printStack(Foam::Ostream&) at ??:? #1 Foam::error::abort() at ??:? #2 Foam::heRhoThermo >, Foam::sensibleEnthalpy> > > >::calculate() at ??:? #3 Foam::heRhoThermo >, Foam::sensibleEnthalpy> > > >::correct() at ??:? #4 ? at ??:? #5 __libc_start_main in "/lib/x86_64-linux-gnu/libc.so.6" #6 ? at ??:?

24 March 2021 0 0 View