Anyone experienced with protein verification tool whatcheck[http://swift.cmbi.ru.nl/gv/whatcheck/]? Their homepage instructions seems blurry to me, looking for tutorials about installation and usage.
I was trying many tutorials for cnn that I've found online but they are not showing good performance. But my dataset is good enough, when I try with knn or mlp in sklearn I'm getting above 98%...
01 February 2018 3,012 5 View
I was studying about ppi prediction with machine learning approach, then the latest development I've found reported 97% accuracy with DVM hereAccurate prediction of protein-protein interactions by...
11 December 2017 6,716 7 View
I was reading some papers about protein-protein interaction prediction using machine learning. I understood that using various algorithms, all the sequences are transformed into equal length...
09 October 2017 6,877 3 View
I'm looking for a tool that can give how many methyl groups, hydroxyl groups etc. are in a compound from it's SMILES, SDF or MOL2 format.
04 May 2017 9,932 5 View
My protein of interest has 3D structure available in pdb. I know about an snp that produces short isoform of that protein. How or using what tool I can produce that isoform as a pdb file?
03 April 2017 2,286 3 View
Is it possible to presume about which Salomonella species present in the sample without using molecular tools like PCR? Just from biochemical tests? If I plan to do PCR for confirming species, how...
09 October 2016 2,202 2 View
I have a list of proteins with their expression metrics. What tools can I use for predicting pathway, cluster analysis etc?
06 July 2016 4,367 2 View
For one of my experiment I need to run a program continuously for a few days. I actually do this in a local cluster. There the head node connects with the slaves with ssh and distribute the work....
04 May 2016 5,779 2 View
I've a receptor and ligand both as pdb file. With mgltools I've converted them to pdbqt. Then performed docking with autodock vina. Now I want my receptor and pdbqt generated by vina to have in a...
01 February 2015 5,001 6 View
I have dataset containing thousands of miRNAs associated with a disease collected from miRTarBase. I need some idea, about what information I can deduce/predict with in-silico/bioinformatic...
01 February 2015 8,780 3 View
I have virus (viral hemorrhagic septicemia virus) in suspension and the experiment will not involve cells. What level of TCID50 is preferred?
11 August 2024 3,115 1 View
I'm working on selecting antibodies against a recombinant protein that has a His-tag. My idea is to first bind the recombinant protein to a HisTRAP column and then use this column for an affinity...
07 August 2024 505 3 View
I am working on Abaqus/Explicit(Quasistatic ) for the deformation of the auxetic structure model. Please explain how the plastic input value should be considered from the true stress-strain curve...
05 August 2024 454 3 View
I aim to be as skeptical as possible regarding whether a pair of orthologous genes results in the same phenotype in their different but related bacterial organisms under similar environmental...
05 August 2024 6,787 4 View
I am working on a SEM model where i have 7 latent variables (6 exogenous and 1 endogenous). In AMOS when I co-vary the exogenous constructs, only 2 paths are coming significant out of 6. But when...
03 August 2024 6,028 4 View
Is it the "elution buffer" or the "dialysis buffer"? Note: I'll be using NanoDrop OneC
01 August 2024 967 3 View
Suppose I am studying the construct of "Academic Motivation" (latent variable) in students, which is measured through three observed variables: "Intrinsic Motivation," "Extrinsic Motivation," and...
31 July 2024 3,913 6 View
I am looking for software to help analyze SELEX NGS data, including alignment, sequence enrichment, and other related tasks. Can anyone recommend suitable tools or software? Best wishes, Waleed
30 July 2024 1,061 5 View
PeptiCloud (www.pepticloud.com) is a bioinformatic platform that allows researchers to organize and share their data for their projects as well as collaborate with others in one place. Through...
28 July 2024 4,762 2 View
Can a researcher use small sample size of 40 while using SEM with bootstrapping of 1000 and is it possible to get published
28 July 2024 4,402 2 View