Drug delivery system- I am asking about chemical reactions that conjugate the PEG to DOX and bromelain
Which mechanism(s) or linker are needed to change a methyl group (-CH3) to a carboxyl or amine groups (-COOH/_NH2)?
01 February 2019 8,092 10 View
I am looking for reviewers for my paper submission. Could you please advice me what I am suppose to do? Thank you in advance.
09 October 2015 355 2 View
Does anybody know that how I can induce immune suppression in balb/c mice using drugs or any other simple method? Needless to say I cannot use nude or SCID mice in our conventional animal lab. On...
08 September 2015 2,893 9 View
I am developing two different cancer models in immunocompetent balb/c mice by subcutaneusly injection of Hela and SK-BR-3 cell lines. Appreciate any suggestions.Is there any option to generate...
07 August 2015 5,653 10 View
The immunocompetent balb/c mice were injected by Hela cell lines. They lost their hair one month after injection, but there is no cancer bumping yet.
07 August 2015 9,068 4 View
Is one time injection of cells enough to establish cancer in mice? is 1* 10^7 cells enough or not ? How detect cancer after injection and how determine that is our interested cancer which...
04 May 2015 367 8 View
I am looking for the method to determine bromelain enzyme concentration in unknown sample using HPLC C18 column. I would be very thankful and appreciative if anyone can help me with method and...
31 December 2014 6,822 5 View
The ―COOH of nanoparticles was activated using EDC/NHS and then covalently attached to the ―NH2 of the enzyme, forming ―CO―NH―. Now, which peaks number will show that the conjugation successfully...
11 December 2014 5,850 9 View
Iron oxide nanoparticles are coated with citric acid and the XRD patterns analysed before and after coating with citric acid. The only difference was in intensity which decrease after coating....
10 November 2014 5,163 8 View
What is the range of saturation magnetization of superparamagnetic nanoparticles? Why sometimes saturation magnetization come down to 1emu, but sometimes is higher than 60 emu. What is the...
10 November 2014 969 19 View
Hello everyone, I recently submitted an article to Geotechnical Engineering (Proceedings of the ICE), and the current status has been listed as "EiC Pre-assessment: Ready" for the past 20 days. I...
10 August 2024 6,493 1 View
Hello everyone, I have recently started using the microtome device for sectioning of paraffin-embedded mice lung. While I had some success in sectioning and observing proper ribbons, some of my...
06 August 2024 666 4 View
I am Looking for a Science Journal with good impact factor and low publication cost to publish a review paper. Your suggestions would be appreciated.
06 August 2024 6,796 3 View
After immunohistochemistry of previously fixed in PFA and EtOH and then frozen 20 μm sections of zebrafish brain, DAPI staining is very weak (right) compared to the same sections stained without...
05 August 2024 9,637 2 View
Are there any statistical methods to justify your sampling technique using SPSS or AMOS?
05 August 2024 9,153 4 View
Brain and body mass together are positively correlated with lifespan (Hofman 1993). The duration of neural development is one of the best predictors of brain size, and conception is the best...
05 August 2024 6,247 3 View
I will be with my students collecting seaweed samples in a marine farm and later we will process this tissue for RNA isolation and further sequencing. Does anyone have tips on how to collect the...
04 August 2024 501 2 View
Better ways to analyze the qualitative and quantitative data in a sequential explanatory mixed method approaches
04 August 2024 2,703 6 View
Any idea about 'International Research Journal of commerce , arts and science? Is it a UGC listed journal? Kindly advice
04 August 2024 7,367 3 View
As authors and academic writers, we usually prepare our manuscript using our own resources. We submit these manuscripts to scientific Journals for peer review and publication sometimes at a fee....
03 August 2024 7,304 2 View