Can someone suggest inhibitors to block double strand breaks or activators that facilitate double stranded break repair process?

05 May 2013 0 710 Report

I noticed upregulated DNA damage (both phospho-Chk1 and phospho-Histone H2A.X) in my systems. This is followed by cycle cycle arrest and decreased CDK1/cyclin B expression. The objective is to decrease DNA damage, which could enhance cell proliferation cycle in my systems.

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How to determine which bacterial virulence factor in relevance to human sepsis or infection regulate my target protein of interest?

How to determine which bacterial virulence factor (bacterial toxins or cell wall components) in relevance to human sepsis or bacterial infection will interact or regulate my target protein of...

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What are the best vectors to express sgrnas + GFP and excluding Cas9?

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01 February 2016 1,859 1 View

Are there any bioinformatics tools or softwares that can locate/identify the site of binding domains between two protein sequences?

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02 March 2014 9,043 0 View

Are there any bioinformatics tools or softwares that can locate/identify the site of binding domain between two protein sequences?

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02 March 2014 5,957 4 View

Can anyone tell me how to identify WXXL motif containing all human proteins from databases?

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02 March 2014 4,779 4 View

How to separate lipid contaminants during protein extraction of animal tissues?

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02 March 2012 1,789 13 View

Enhanced Yellow Fluorescent Protein (Aequorea victoria) DNA sequence?

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03 March 2021 3,568 1 View

Does anyone know HRM channel in a 2 plex QIAGEN Rotor- Gene Q qPCR can be used as a separate channel?

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01 March 2021 8,544 1 View

Which cell line should we use to perform biological dosimetry experiments?

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For modelling epoxy-based matrices (in composites), which model in ABAQUS is the most suitable, Concrete damaged plasticity or Drucker-Prager model?

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28 February 2021 5,415 1 View

B-mercaptoethanol (BME) protocol?

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27 February 2021 5,028 2 View

Calculating volume of DNA required from DNA concentration?

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26 February 2021 5,029 2 View

Has anyone used the Illumina ITS1 primer sets?

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25 February 2021 6,969 3 View

Errors in DNA sequences?

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24 February 2021 4,397 3 View

Quantifying leaking DNA from bacteria - what's the secret?

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24 February 2021 2,006 2 View

How the Ground Plane implantation is performed without damaging (and w/o varying the undoped nature) the top Si (8-10 nm) in FDSOI technology ?

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24 February 2021 5,974 4 View