Are there any bioinformatics tools or softwares that can locate/identify the site of binding domain between two protein sequences?

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Kishna Vijayaraghavan

Dear Angara,

U can either use ExPASY-PROSITE /CATH-SCOP tools.

Sureshbabu Angara

Hi Shandar Ahmad,

I tried your tool. How to assess total pair wise scores in relation to binding/interaction. Is there any acceptable range or score to say that the two proteins interaction is highly likely?

Sidra Rafi

u can try DogSite Scorer

http://dogsite.zbh.uni-hamburg.de/

hope it help

Sanjiv Kumar

Here's a list of tools available to check the binding site prediction among two interacting proteins http://www.bioinformatictools.blogspot.in/2012/02/in-silico-binding-site-prediction-in.html I used CASTp for my work long back and it gives decent output. You can try them and let us know if it works for you. Hope this helps.