I want to do an alignment study for a ligand I have on an already published pharmacophore model by another group. Are there any available ways to import this pharmacophore model to Maestro to do the alignment study on it? Or do I have to contact the paper authors to send me the model?
Also, are there any other suggestions for doing this alignment for my ligand on this already published pharmacophore on other interfaces?
Technically, you can reproducer the features if the authors provide the test set, training set, and you used the same software. But usually, the default pharmacophore features required refinement and some editing to make the features more specific or general. Thus, it is better to contact the authors if you want the exactly same pharmacophore model as from the paper.
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