14 March 2019 3 2K Report

I am interested whether adding NADH to culture medium would lead to its uptake into the cytoplasm. I'm guessing it's not permeable to the cell wall/plasma membrane, but might there be active transporters?

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How to compute assembly index for raster data?

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What effects does the zero-interest policy have on risk taking behavior of private investors, especially large ones who can afford high losses?

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30 January 2022 1,124 6 View

Are the venture capital and private equity firms a new vehicle to trigger a future financial crisis?

Shadow banks, which played a key role in triggering the recent global financial crisis, and venture capital companies that followed, have partly displaced traditional banks from corporate...

30 January 2022 6,333 8 View

Did anyone use DreamPlace along with Cadence Innovus?

I'm not yet aware of an existing (open) implementation that combines DREAMPlace with a commercial tooling for the Routing and Signoff. Dear crowd: Do you know anything about that? Link to...

03 November 2021 632 0 View

Calculate Implosion or Explosion model in spread (would take a swap between two variables)?

Can you explain a list of information and matter that is spread from the outer limit to the inner point in a polarcoordinate system - the outher way around is a norlmal incrementing model while...

23 June 2020 1,633 0 View

Why is ccdb toxin not killing susceptible strains of E.coli?

Hi hive, We are trying to use ccdb as a counter selection marker. We are using the cassette from this paper, which should be highly expressed: A new method to customize protein expression vectors...

22 June 2020 5,231 5 View

Appropriate statistical test for within-group comparisons of questionnaires?

Dear colleagues, I am trying to determine the appropriate statistical test for my problem. I have read several discussions on the topic here, however was unable to extract an answer, and so I...

03 May 2020 6,448 10 View

How to interpret transition states whose Gibbs-energies are higher than the Gibbs-energies of their corresponding ground states?

I am performing DFT-calculations (gamess-us) on a reaction: ground state 1 -> transitition state -> ground state 2. (in short: gs1 -> ts -> gs2.) ts is only 0.3 kcal/mol higher in...

16 February 2020 2,414 1 View

Open datasets for Machine Learning in geotechnics / engineering geology?

Machine learning has proven to be very successfull in many disciplines and the general development is surely furthered by openly accesible algorithms and datasets for the whole community to work...

23 October 2019 7,070 19 View

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