In many instances a small amount (5-30 ML.) of blood from the external surface of body is let out. In the process of homeostasis, some chemical parameters might change. I wish to know- what are the changes in the biochemistry of blood that take place eg. pH and after how much time does the compensatory mechanism stop?
The question is not clear. if u r asking what changes happen to the blood that was drawn out. Actually a lot happens, starting from pH, protein content, enzyme activity, concentrations of Ions (esp. Na+, Cl-),. Factors that affect are, temperature, prolonged delay after drawing the blood etc. The composition is also differs on what blood you draw: venous or arterial blood. type of sample: Heparinized blood or coagulated blood etc.
There is virtually no impact on body physiology, biochemical, hemostatic, or metabolic activity/systems with blood loss up to 15 percent of blood volume (similar to typical blood donor). An excellent brief review of hemorrhagic shock "The Body's Response to Blood Loss" by Garrioch in Vox Sanguinis (2004) full article at:
http://baata.org/polezni/blood%20loss.pdf
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