The answer to this question is key to better understand the cancer risk associated with some germline polymorphisms and its relation to race and ethnicity.
Article Is p53 Polymorphism Maintained by Natural Selection?
Probably you are aware of the IARC TP53 database but I mention it anyway: http://p53.iarc.fr/RefsHighlights.aspx
There is also the "p53_web_site" http://p53.free.fr/index.html but this was last updated 3 years ago.
There was a recent paper that looked at this in breast cancer and Li Fraumeni Syndrome:
http://www.ncbi.nlm.nih.gov/pubmed/25564201
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