Are the amino groups in nucleobases diazotizable?

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Request for a sample of NSERC grant application?

While I am looking for academic positions in Canada, they are constantly asking for a research proposal in NSERC format. I never had an experience of making a proposal in that format. Hence, I...

11 December 2019 4,029 2 View

Does anyone have a "tried and true" method for cleaning the thermal residue from NaH2PO2?

Whenever I pyrolyzed NaH2PO2, I am facing difficulties in cleaning the white left over residue (may be phosphates) in the tube. So, I am looking for any effective cleaning protocols to get rid of...

11 December 2019 969 7 View

Does anyone have a "tried and true" method for making MoS2 quantum dots?

Most of the literature reports that I came across are vague, especially the separation process. So, I am looking for the tried and true protocols which can yield

10 November 2019 8,698 2 View

What are the thermal degradation products of 6-mercaptopurine?

I am looking for the thermal degradation pathway and products of 6-mercaptopurine (Temp.: 200-1000 Celsius, Inert atmosphere). Any relevant reading suggestions are also much appreciated. Thanks.

03 April 2019 8,728 3 View

Does anyone have a "tried and true" method for solubilizing Guanine in ionic liquids?

I would like to dissolve (even partly) guanine in ionic liquids. Any relevant reading suggestions are also much appreciated. Thanks.

02 March 2019 3,817 3 View

Which nucleobase has reversible redox activity?

I am looking for a nucleobase (utmost its derivative) which shows reversible redox activity. I went through some of the literature and found out that the redox features of nucleobases are very...

31 December 2018 4,879 3 View

Does anyone have a "tried and true" method for solubilizing WO3?

From literature, I found that WO3 can be solubilized in hot NH4OH. But, I am unable to find the relevant amounts and conditions. As I want to avoid HF, any relevant reading suggestions are also...

10 November 2018 8,028 2 View

What are the metal chlorides that react with water?

I am looking for the metal chlorides (preferably corrosive oxidants) that aggressively react with water to give HCl. Some of the examples that I am aware of are AlCl3, WCl4, WCl6, TaCl5, ZrCl3 and...

10 November 2018 7,286 6 View

Which lithium salt produce metallic lithium with gaseous byproducts upon thermal decomposition?

The purpose is Li-intercalation, for which, I currently use LiBH4 or n-BuLi. As these chemicals are difficult to handle, I am looking for alternatives. The temperature range I am interested in is...

09 October 2018 1,871 4 View

What is the purpose of freezing the samples in liquid nitrogen during MOFs synthesis?

In several readings, I noticed that the samples were frozen in liquid nitrogen before heating them in autoclaves, especially if the solvent is DMF, NMP etc. As I am novice in this direction, can...

06 July 2018 5,652 4 View

• What the possible Persistent Organic Pollutants and Heavy metals present in fluorspar, sediments, and water bodies around its mining area?

Approximate concentrations are require in compared with the WHO permissible limts

11 August 2024 2,723 1 View

Can I base on reverse DNA sequences to perform alignment, convert to amino acids and GenBank submission?

I have reverse sequences (AB1 format), can I base on reverse DNA sequences to perform nucleotide alignment, convert nucleotides to amino acids and deposit the sequence in GenBank database?

11 August 2024 5,138 1 View

Basis set and input instruction to calculate HOMO and LUMO using Orca for Imidazolium based organic salts?

Hey there, As a synthetic chemist delving into theoretical calculations for my imidazolium-based organic molecules, I would greatly appreciate any guidance on the appropriate input instructions...

09 August 2024 5,444 7 View

I can't see the ssDNA band after performing asymmetric PCR. Is there any way to do this?

After performing symmetric PCR, PCR purification was performed. Afterwards, asymmetric PCR was performed using the PCR purification product as a template, but no ssDNA band was confirmed in the...

08 August 2024 1,668 3 View

How to calculate CCS for Sodiated adduct ions and Multiply Charged Ions?

I'm currently working on calculating the collision cross section (CCS) for various ions, and I'm facing challenges when dealing with sodiated and multiply charged ions. Most of the resources I’ve...

08 August 2024 8,329 0 View

Does crude extraction using NaOH and Tris work well with Fungi?

I'm trying to find a DNA extraction method for fungi that does not require equipment and heating. Is there anyone who can suggest an alternative option? Thank you

08 August 2024 4,733 2 View

Separation of organic acids-HPLC?

Hello What should be done to separate and identify organic acids in HPC when their RetTime is the same?Like oxalic acid with Propanoic Acid.or acids that have a very close RetTime.

07 August 2024 8,782 3 View

Why after performing site directed mutagenesis ,I don't see any colony after transformation?

I want to introduce a point mutation (change in one nucleotide) into my gene of interest (DNA binding domain) I have designed primers as recommended on the Data sheet of the kit : -Both primers...

05 August 2024 9,059 3 View

Determining the worth of a point improvement in Hamilton Depression Scale?

Dear readers, Thanks for your attention. I am wondering about the health economic problem of quantifying the value of interventions which a) prevent, b) improve symptom profile and c) ultimately...

05 August 2024 3,246 1 View

How to convert g/kg Humic acid dose to kg/ha?

I used humic acid at 0.044 g/kg soil in my pot experiment. But finally, I have to recommend kg/ha. Each pot's soil weight was 11 kg. What is the solution?

02 August 2024 7,186 6 View