Total RNA was extracted from FFPE blocks and concentrations were measured using nanodrop. 260/280 looked normal (1.89-2.06). I treated these samples with DNAseI from Invitrogen and my ratios increased to 2.1-2.4. My blank included the same concentrations of enzyme/buffer/EDTA  that my samples have. I called tech support and they didn't have an explaination. Has anyone ever encountered a similar issue? And if so, what steps did you take to fix the issue. I am planning on using these samples in a qPCR reaction and want to make sure I have good quality RNA before proceeding. Any help would be appreciated.