“Formulation and evaluation of herbal-based drug delivery systems for enhanced therapeutic efficacy.”

awesome—great choice 🎯

(quick note on spelling: Withania somnifera a.k.a. Ashwagandha, and Vitex negundo a.k.a. Nirgundi.)

Here’s a complete, publication-ready roadmap for an anti-inflammatory nanoemulsion combining these two:

Thesis framing (pick one title)

Dual-Herb Nanoemulsion of Withania somnifera and Vitex negundo for Topical Anti-inflammatory Therapy: Formulation, Optimization, and Pharmacodynamic Evaluation

Quality-by-Design Development of Ashwagandha–Nirgundi Nanoemulgel: Stability, Skin Permeation, and Mechanistic Anti-inflammatory Studies

Co-loaded Phyto-nanoemulsion Targeting COX-2/NF-κB Pathways: From Marker-based Standardization to Efficacy

Aim

To formulate and optimize a co-loaded nanoemulsion (converted to nanoemulgel for topical use) of W. somnifera and V. negundo extracts to enhance solubility, skin permeation, and anti-inflammatory efficacy with acceptable stability and safety.

Hypotheses

H1: Nanoemulsification of both extracts reduces droplet size (

Pharmacokinetic and Pharmacodynamic Study of Herbal Nanoemulsion for Anti-inflammatory Activity

Single or combined formulation , evaluation of herbal based drug through ADMETand Pharmacokinetics analysis can establish increased therapeutic potential.