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Questions related to Bioinformatics and Computational Biology
- Since I have very less background in bioinformatics, I find it hard to understand some of things. Looking forward towards kind replies. Thanking in anticipation :)
01 January 2018 4,818 5 View
i have the structure of unbound protein, ligand and protein -ligand complex?
01 January 2018 7,523 8 View
I have 12 species from same genus. For supermatrix approach we generally use the multiple sequence alignment single copy orthologs sequences then concatenate them and remove the badly aligned...
12 December 2017 4,052 4 View
Dear RG Members? I need to install mpci package on HPC cluster. Currently working on gromacs 5.0. Any suggestions?
12 December 2017 5,414 2 View
Like the title, anyone could suggest me some quality conferences in bioinformatics and computational biology field hosted before Feb 2018? Thanks a lot!
10 October 2017 459 3 View
What is the difference between RNA sequencing and Exome Capture RNA Sequencing and how it differentiated with exome and RNA Seq?
10 October 2017 8,992 7 View
what does it mean. will it affect my docking results. if it affects how to prevent them ??
10 October 2017 3,513 4 View
I read several papers where researchers use several strains of same species for analysis of recombination or selection pressure however there are few papers in which researchers use the multiple...
10 October 2017 9,012 4 View
Can anyone suggest books/papers which clearly explains pi-alkyl, pi-pi T shaped and pi-Sulphur interaction?
10 October 2017 2,861 4 View
Say for example a combination of MATK and RBCL gene in plants ?
10 October 2017 1,741 3 View
Bootstrap value X mega software
10 October 2017 8,754 2 View
I am planning to tag a protein with mCherry using CRISPR/CAS9 method. I need to know if adding the mCherry seq. on 3'UTR can affect the functionality of protein or if I should add the mCherry...
10 October 2017 9,669 7 View
02 October 2017 8,394 3 View
Hello, I am using surface plasmon resonance for cancer biomarker detection. I know the dynamic measurement helps in understanding the association and dissociation of biomolecules to the sensor...
17 September 2017 3,373 3 View
Can anyone explain it with an example and steps followed?
09 September 2017 1,931 4 View
The DUD-E paper https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3405771/ says that their decoys have similar physicochemical properties but different 2-D topologies in relation to the ligands. ¿What...
09 September 2017 9,054 2 View
How can we get a single sequence from two separate forward and reverse sequenced PCR product ? Is it possible by bioedit software?
09 September 2017 6,081 2 View
Can we use post-mortem peripheral blood using for disease related genetic variant study (identify the SNP)?
01 September 2017 3,394 3 View
Senior BD, Research Fellow needed, candidates should have a PhD in Biology, genetics, aquaculture，microbiology, virology, molecular biology, computational biology, bioinformatics, marine biology,...
31 August 2017 7,183 4 View
Which file produces the sub-population when running 'Structure software?' I am assuming the "Q matrix" file. Could someone familiar confirm?
30 August 2017 1,075 1 View
08 August 2017 2,911 5 View
08 August 2017 8,807 1 View
RNA-Seq is well known for calculating transcript expression. But, researches also do variant calling on RNA-seq data. In such case all mutations can't be identified due to alternative splicing....
08 August 2017 8,428 8 View
The software should work like this: I choose a molecule; and then the software scans a whole library of many many molecules, and then it quantifies the overlap of each one of them with my target...
08 August 2017 9,170 3 View